Team game results - 2021 Houston
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/1/2021 | | @ | Oak | W | 8-5 | | Greinke, Z | R | Greinke, Z | | Bassitt, C | R |
| 4/2/2021 | | @ | Oak | W | 10-2 | | Javier, C | R | Bielak, B | | Luzardo, J | L |
| 4/3/2021 | | @ | Oak | W | 4-3 | | McCullers, L | R | Abreu, B | Pressly, R | Irvin, C | L |
| 4/4/2021 | | @ | Oak | L | 6-15 | | Urquidy, J | R | Urquidy, J | | Manaea, S | L |
| 4/5/2021 | | @ | LAA | W | 11-7 | | Garcia, L | R | Stanek, R | | Quintana, J | L |
| 4/6/2021 | | @ | LAA | W | 7-3 | | Greinke, Z | R | Greinke, Z | | Bundy, D | R |
| 4/8/2021 | | | Oak | W | 6-2 | | Javier, C | R | Javier, C | | Irvin, C | L |
| 4/9/2021 | | | Oak | W | 4-2 | | McCullers, L | R | McCullers, L | Pressly, R | Manaea, S | L |
| 4/10/2021 | | | Oak | W | 12-3 | | Urquidy, J | R | Urquidy, J | | Montas, F | R |
| 4/12/2021 | | | Det | W | 6-5 | | Greinke, Z | R | Stanek, R | | Mize, C | R |
| 4/13/2021 | | | Det | W | 7-4 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Boyd, M | L |
| 4/14/2021 | | | Det | W | 8-4 | | McCullers, L | R | McCullers, L | | Fulmer, M | R |
| 4/16/2021 | | @ | Sea | W | 2-1 | | Urquidy, J | R | Stanek, R | Pressly, R | Kikuchi, Y | L |
| 4/17/2021 | | @ | Sea | W | 9-3 | | Greinke, Z | R | Greinke, Z | | Flexen, C | R |
| 4/18/2021 | | @ | Sea | W | 3-1 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Margevicius, N | L |
| 4/20/2021 | | @ | Col | L | 4-5 | 10 | Garcia, L | R | Raley, B | | Gray, J | R |
| 4/21/2021 | | @ | Col | L | 2-6 | | Urquidy, J | R | Urquidy, J | | Gomber, A | L |
| 4/22/2021 | | | LAA | W | 5-0 | | Javier, C | R | Javier, C | | Cobb, A | R |
| 4/23/2021 | | | LAA | L | 0-1 | | Greinke, Z | R | Greinke, Z | | Heaney, A | L |
| 4/24/2021 | | | LAA | W | 12-3 | | Odorizzi, J | R | Odorizzi, J | | Canning, G | R |
| 4/25/2021 | | | LAA | W | 2-0 | | McCullers, L | R | McCullers, L | Pressly, R | Bundy, D | R |
| 4/26/2021 | | | Sea | L | 2-5 | | Urquidy, J | R | Urquidy, J | | Sheffield, J | L |
| 4/27/2021 | | | Sea | W | 7-4 | | Javier, C | R | Solomon, P | | Gonzales, M | L |
| 4/28/2021 | | | Sea | W | 7-3 | | Greinke, Z | R | Greinke, Z | | Dunn, J | R |
| 4/29/2021 | | | Sea | W | 6-1 | | Garcia, L | R | Garcia, L | | Kikuchi, Y | L |
| 4/30/2021 | | @ | Tam | W | 9-2 | | McCullers, L | R | McCullers, L | | Yarbrough, R | L |
| 5/1/2021 | | @ | Tam | W | 9-3 | | Urquidy, J | R | Urquidy, J | | Fleming, J | L |
| 5/2/2021 | | @ | Tam | L | 1-2 | | Javier, C | R | Javier, C | | Hill, R | L |
| 5/4/2021 | | @ | NYA | L | 3-4 | | Greinke, Z | R | Greinke, Z | | German, D | R |
| 5/5/2021 | | @ | NYA | W | 6-5 | | Garcia, L | R | Garcia, L | Pressly, R | Montgomery, J | L |
| 5/6/2021 | | @ | NYA | W | 5-1 | | McCullers, L | R | McCullers, L | | Cole, G | R |
| 5/7/2021 | | | Tor | W | 3-2 | | Urquidy, J | R | Urquidy, J | Stanek, R | Stripling, R | R |
| 5/8/2021 | | | Tor | L | 3-7 | | Javier, C | R | Javier, C | | Matz, S | L |
| 5/9/2021 | | | Tor | W | 5-4 | 15 | Greinke, Z | R | Emanuel, K | | Pearson, N | R |
| 5/10/2021 | | | LAA | W | 11-5 | | Garcia, L | R | Garcia, L | | Guerra, J | R |
| 5/11/2021 | | | LAA | W | 7-2 | | McCullers, L | R | McCullers, L | | Ohtani, S | R |
| 5/12/2021 | | | LAA | W | 13-9 | | Urquidy, J | R | Urquidy, J | | Heaney, A | L |
| 5/13/2021 | | | Tex | L | 2-4 | | Javier, C | R | Bielak, B | | Foltynewicz, M | R |
| 5/14/2021 | | | Tex | L | 2-5 | | Greinke, Z | R | Greinke, Z | | Benjamin, W | L |
| 5/15/2021 | | | Tex | W | 9-2 | | Garcia, L | R | Garcia, L | | Dunning, D | R |
| 5/16/2021 | | | Tex | W | 8-0 | | McCullers, L | R | McCullers, L | | Gibson, K | R |
| 5/18/2021 | | @ | Oak | W | 6-1 | | Javier, C | R | Javier, C | | Manaea, S | L |
| 5/19/2021 | | @ | Oak | W | 9-2 | | Greinke, Z | R | Greinke, Z | | Montas, F | R |
| 5/20/2021 | | @ | Oak | L | 2-6 | | Garcia, L | R | Garcia, L | | Irvin, C | L |
| 5/21/2021 | | @ | Tex | L | 8-17 | | Ivey, T | R | Ivey, T | | Gibson, K | R |
| 5/22/2021 | | @ | Tex | W | 10-0 | | McCullers, L | R | McCullers, L | | Lyles, J | R |
| 5/23/2021 | | @ | Tex | W | 6-3 | | Javier, C | R | Javier, C | Pressly, R | Foltynewicz, M | R |
| 5/25/2021 | | | LAN | L | 1-2 | | Greinke, Z | R | Greinke, Z | | Kershaw, C | L |
| 5/26/2021 | | | LAN | L | 2-10 | | Garcia, L | R | Garcia, L | | Bauer, T | R |
| 5/28/2021 | | | SD | W | 10-5 | | Valdez, F | L | Valdez, F | | Lamet, D | R |
| 5/29/2021 | | | SD | W | 7-6 | | Odorizzi, J | R | Stanek, R | Pressly, R | Darvish, Y | R |
| 5/30/2021 | | | SD | W | 8-5 | | Greinke, Z | R | Greinke, Z | Pressly, R | Snell, B | L |
| 5/31/2021 | | | Bos | L | 2-9 | | Urquidy, J | R | Urquidy, J | | Rodriguez, E | L |
| 6/1/2021 | | | Bos | W | 6-1 | | Garcia, L | R | Garcia, L | | Richards, G | R |
| 6/2/2021 | | | Bos | W | 4-1 | | Valdez, F | L | Valdez, F | Pressly, R | Pivetta, N | R |
| 6/3/2021 | | | Bos | L | 0-4 | | Odorizzi, J | R | Odorizzi, J | | Perez, M | L |
| 6/4/2021 | | @ | Tor | W | 5-4 | 10 | Greinke, Z | R | Javier, C | Pressly, R | Ryu, H | L |
| 6/5/2021 | | @ | Tor | W | 11-7 | | Urquidy, J | R | Rodriguez, N | | Stripling, R | R |
| 6/6/2021 | | @ | Tor | L | 6-11 | | Garcia, L | R | Garcia, L | | Matz, S | L |
| 6/8/2021 | | @ | Bos | W | 8-3 | | Valdez, F | L | Valdez, F | | Perez, M | L |
| 6/9/2021 | | @ | Bos | L | 5-7 | | Odorizzi, J | R | Odorizzi, J | | Eovaldi, N | R |
| 6/10/2021 | | @ | Bos | W | 4-2 | | Greinke, Z | R | Greinke, Z | Pressly, R | Rodriguez, E | L |
| 6/11/2021 | | @ | Min | W | 10-4 | 10 | Urquidy, J | R | Stanek, R | | Ober, B | R |
| 6/12/2021 | | @ | Min | W | 5-3 | | Garcia, L | R | Garcia, L | Pressly, R | Berrios, J | R |
| 6/13/2021 | | @ | Min | L | 6-7 | | Valdez, F | L | Pressly, R | | Pineda, M | R |
| 6/15/2021 | | | Tex | L | 1-8 | | McCullers, L | R | McCullers, L | | Gibson, K | R |
| 6/16/2021 | | | Tex | L | 3-10 | | Greinke, Z | R | Greinke, Z | | Lyles, J | R |
| 6/17/2021 | | | ChA | W | 6-5 | | Urquidy, J | R | Stanek, R | Pressly, R | Cease, D | R |
| 6/18/2021 | | | ChA | W | 4-1 | | Garcia, L | R | Garcia, L | Pressly, R | Rodon, C | L |
| 6/19/2021 | | | ChA | W | 12-2 | | Valdez, F | L | Valdez, F | Garza, R | Lynn, L | R |
| 6/20/2021 | | | ChA | W | 4-3 | | McCullers, L | R | Taylor, B | Pressly, R | Keuchel, D | L |
| 6/21/2021 | | @ | Bal | W | 7-4 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Akin, K | L |
| 6/22/2021 | | @ | Bal | L | 2-5 | | Greinke, Z | R | Greinke, Z | | Lopez, J | R |
| 6/23/2021 | | @ | Bal | W | 8-0 | | Urquidy, J | R | Urquidy, J | | Eshelman, T | R |
| 6/24/2021 | | @ | Det | L | 4-9 | | Garcia, L | R | Garcia, L | | Urena, J | R |
| 6/26/2021 | 1 | @ | Det | W | 1-0 | 7 | Valdez, F | L | Valdez, F | | Mize, C | R |
| 6/26/2021 | 2 | @ | Det | W | 10-2 | 7 | McCullers, L | R | McCullers, L | | Peralta, W | R |
| 6/27/2021 | | @ | Det | L | 2-9 | | Odorizzi, J | R | Odorizzi, J | | Skubal, T | L |
| 6/28/2021 | | | Bal | W | 11-3 | | Greinke, Z | R | Greinke, Z | | Eshelman, T | R |
| 6/29/2021 | | | Bal | W | 10-0 | | Urquidy, J | R | Urquidy, J | | Lakins, T | R |
| 6/30/2021 | | | Bal | L | 10-12 | | Garcia, L | R | Garcia, L | | Harvey, M | R |
| 7/1/2021 | | @ | Cle | W | 3-2 | 11 | Valdez, F | L | Pressly, R | | Mejia, J | R |
| 7/2/2021 | | @ | Cle | W | 9-3 | | McCullers, L | R | McCullers, L | | Hentges, S | L |
| 7/3/2021 | | @ | Cle | L | 1-6 | | Odorizzi, J | R | Odorizzi, J | | Morgan, E | R |
| 7/4/2021 | | @ | Cle | L | 1-3 | | Greinke, Z | R | Taylor, B | | Quantrill, C | R |
| 7/6/2021 | | | Oak | L | 3-6 | | Valdez, F | L | Valdez, F | | Bassitt, C | R |
| 7/7/2021 | | | Oak | L | 1-4 | | Garcia, L | R | Garcia, L | | Manaea, S | L |
| 7/8/2021 | | | Oak | W | 10-3 | | McCullers, L | R | McCullers, L | | Montas, F | R |
| 7/9/2021 | | | NYA | L | 4-6 | | Odorizzi, J | R | Odorizzi, J | | Cortes, N | L |
| 7/10/2021 | | | NYA | W | 5-3 | | Greinke, Z | R | Greinke, Z | Pressly, R | Cole, G | R |
| 7/11/2021 | | | NYA | W | 3-2 | | Valdez, F | L | Valdez, F | Javier, C | Taillon, J | R |
| 7/16/2021 | | @ | ChA | L | 2-4 | | McCullers, L | R | McCullers, L | | Cease, D | R |
| 7/17/2021 | | @ | ChA | W | 6-0 | | Odorizzi, J | R | Odorizzi, J | | Giolito, L | R |
| 7/18/2021 | | @ | ChA | L | 0-2 | | Valdez, F | L | Valdez, F | | Rodon, C | L |
| 7/19/2021 | | | Cle | L | 2-3 | | Greinke, Z | R | Stanek, R | | Mejia, J | R |
| 7/20/2021 | | | Cle | W | 3-2 | | Garcia, L | R | Bielak, B | Pressly, R | McKenzie, T | R |
| 7/21/2021 | | | Cle | L | 0-3 | | McCullers, L | R | Abreu, B | | Morgan, E | R |
| 7/23/2021 | | | Tex | W | 4-3 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Allard, K | L |
| 7/24/2021 | | | Tex | L | 0-2 | | Valdez, F | L | Valdez, F | | Gibson, K | R |
| 7/25/2021 | | | Tex | L | 4-6 | | Greinke, Z | R | Raley, B | | Hearn, T | L |
| 7/26/2021 | | @ | Sea | W | 9-7 | | Garcia, L | R | Garcia, L | | McCaughan, D | R |
| 7/27/2021 | | @ | Sea | W | 15-8 | | McCullers, L | R | McCullers, L | | Flexen, C | R |
| 7/28/2021 | | @ | Sea | W | 4-1 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Kikuchi, Y | L |
| 7/30/2021 | | @ | SF | W | 6-5 | | Valdez, F | L | Valdez, F | Pressly, R | Gausman, K | R |
| 7/31/2021 | | @ | SF | L | 0-7 | | Greinke, Z | R | Greinke, Z | | Wood, A | L |
| 8/1/2021 | | @ | SF | L | 3-5 | | Garcia, L | R | Graveman, K | | Webb, L | R |
| 8/3/2021 | | @ | LAN | L | 5-6 | 13 | McCullers, L | R | Abreu, B | | Buehler, W | R |
| 8/4/2021 | | @ | LAN | L | 2-3 | 10 | Odorizzi, J | R | Montero, R | | Scherzer, M | R |
| 8/5/2021 | | | Min | L | 2-5 | | Valdez, F | L | Valdez, F | | Jax, G | R |
| 8/6/2021 | | | Min | L | 3-7 | | Greinke, Z | R | Greinke, Z | | Ober, B | R |
| 8/7/2021 | | | Min | W | 6-2 | | Garcia, L | R | Garcia, L | | Pineda, M | R |
| 8/8/2021 | | | Min | L | 4-7 | | McCullers, L | R | Taylor, B | | Maeda, K | R |
| 8/10/2021 | | | Col | W | 3-2 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Gray, J | R |
| 8/11/2021 | | | Col | W | 4-1 | | Valdez, F | L | Valdez, F | Stanek, R | Senzatela, A | R |
| 8/13/2021 | | @ | LAA | L | 2-3 | | Greinke, Z | R | Greinke, Z | | Sandoval, P | L |
| 8/14/2021 | | @ | LAA | W | 7-2 | | Garcia, L | R | Garcia, L | | Barria, J | R |
| 8/15/2021 | | @ | LAA | W | 15-3 | | McCullers, L | R | McCullers, L | | Detmers, R | L |
| 8/16/2021 | | @ | KC | L | 0-2 | | Odorizzi, J | R | Odorizzi, J | | Hernandez, C | R |
| 8/17/2021 | | @ | KC | W | 4-2 | | Valdez, F | L | Valdez, F | Pressly, R | Lynch, D | L |
| 8/18/2021 | | @ | KC | W | 8-5 | 10 | Greinke, Z | R | Pressly, R | | Singer, B | R |
| 8/19/2021 | | @ | KC | L | 5-12 | | Garcia, L | R | Garcia, L | | Minor, M | L |
| 8/20/2021 | | | Sea | W | 4-0 | | McCullers, L | R | McCullers, L | | Kikuchi, Y | L |
| 8/21/2021 | | | Sea | L | 2-10 | | Odorizzi, J | R | Odorizzi, J | | Gilbert, L | R |
| 8/22/2021 | | | Sea | L | 2-12 | | Valdez, F | L | Valdez, F | | Anderson, T | L |
| 8/23/2021 | | | KC | L | 5-7 | | Greinke, Z | R | Pressly, R | | Lynch, D | L |
| 8/24/2021 | | | KC | L | 1-3 | | Garcia, L | R | Garcia, L | | Singer, B | R |
| 8/25/2021 | | | KC | W | 4-2 | 10 | McCullers, L | R | Maton, P | | Minor, M | L |
| 8/27/2021 | | @ | Tex | W | 7-3 | | Odorizzi, J | R | Odorizzi, J | | Otto, G | R |
| 8/28/2021 | | @ | Tex | L | 2-3 | | Valdez, F | L | Stanek, R | | Allard, K | L |
| 8/29/2021 | | @ | Tex | W | 5-3 | | Greinke, Z | R | Greinke, Z | Pressly, R | Hearn, T | L |
| 8/30/2021 | | @ | Sea | L | 2-3 | | Garcia, L | R | Stanek, R | | Flexen, C | R |
| 8/31/2021 | | @ | Sea | W | 6-0 | | McCullers, L | R | McCullers, L | | Kikuchi, Y | L |
| 9/1/2021 | | @ | Sea | W | 10-1 | | Odorizzi, J | R | Odorizzi, J | | Gilbert, L | R |
| 9/3/2021 | | @ | SD | W | 7-4 | | Urquidy, J | R | Urquidy, J | Pressly, R | Arrieta, J | R |
| 9/4/2021 | | @ | SD | L | 0-7 | | Valdez, F | L | Valdez, F | | Musgrove, J | R |
| 9/5/2021 | | @ | SD | L | 0-6 | | Garcia, L | R | Garcia, L | | Paddack, C | R |
| 9/6/2021 | | | Sea | L | 3-4 | | McCullers, L | R | McCullers, L | | Kikuchi, Y | L |
| 9/7/2021 | | | Sea | W | 7-6 | | Odorizzi, J | R | Pressly, R | | Gilbert, L | R |
| 9/8/2021 | | | Sea | W | 12-4 | | Urquidy, J | R | Urquidy, J | | Anderson, T | L |
| 9/10/2021 | | | LAA | W | 4-3 | | Valdez, F | L | Valdez, F | Pressly, R | Ohtani, S | R |
| 9/11/2021 | | | LAA | W | 3-2 | | Garcia, L | R | Garcia, L | Pressly, R | Suarez, J | L |
| 9/12/2021 | | | LAA | W | 4-2 | | McCullers, L | R | Garcia, Y | Pressly, R | Barria, J | R |
| 9/13/2021 | | @ | Tex | L | 3-4 | | Odorizzi, J | R | Stanek, R | | Howard, S | R |
| 9/14/2021 | | @ | Tex | L | 1-4 | | Greinke, Z | R | Greinke, Z | | Lyles, J | R |
| 9/15/2021 | | @ | Tex | W | 10-3 | | Urquidy, J | R | Urquidy, J | | Arihara, K | R |
| 9/16/2021 | | @ | Tex | L | 4-6 | | Garcia, L | R | Garcia, Y | | Otto, G | R |
| 9/17/2021 | | | Ari | W | 8-6 | | Bielak, B | R | James, J | Pressly, R | Bumgarner, M | L |
| 9/18/2021 | | | Ari | L | 3-4 | | McCullers, L | R | Garcia, Y | | Castellanos, H | R |
| 9/19/2021 | | | Ari | L | 5-8 | | Greinke, Z | R | Pressly, R | | Gallen, Z | R |
| 9/20/2021 | | @ | LAA | W | 9-4 | | Valdez, F | L | Valdez, F | | Barria, J | R |
| 9/21/2021 | | @ | LAA | W | 7-6 | | Urquidy, J | R | Urquidy, J | Pressly, R | Naughton, P | L |
| 9/22/2021 | | @ | LAA | W | 9-7 | 11 | Garcia, L | R | Pressly, R | | Junk, J | R |
| 9/23/2021 | | @ | LAA | L | 2-4 | | McCullers, L | R | Taylor, B | | Cobb, A | R |
| 9/24/2021 | | @ | Oak | L | 1-2 | | Bielak, B | R | Raley, B | | Montas, F | R |
| 9/25/2021 | | @ | Oak | W | 3-0 | | Valdez, F | L | Valdez, F | Pressly, R | Manaea, S | L |
| 9/26/2021 | | @ | Oak | W | 4-1 | | Odorizzi, J | R | Odorizzi, J | Pressly, R | Blackburn, P | R |
| 9/28/2021 | | | Tam | L | 2-8 | | Urquidy, J | R | Urquidy, J | | Wacha, M | R |
| 9/29/2021 | | | Tam | L | 1-6 | | Garcia, L | R | Garcia, L | | Rasmussen, D | R |
| 9/30/2021 | | | Tam | L | 2-5 | | McCullers, L | R | McCullers, L | | McHugh, C | R |
| 10/1/2021 | | | Oak | L | 4-5 | | Valdez, F | L | Valdez, F | | Manaea, S | L |
| 10/2/2021 | | | Oak | L | 6-11 | | Odorizzi, J | R | Odorizzi, J | | Blackburn, P | R |
| 10/3/2021 | | | Oak | W | 5-4 | | Urquidy, J | R | Pressly, R | | Irvin, C | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/1/2021 | | @ | Oak | W | Altuve, J | 8 | 5 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/2/2021 | | @ | Oak | W | Correa, C | 10 | 2 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/3/2021 | | @ | Oak | W | Tucker, K | 4 | 3 | 3 | 0 | 1.000 | 3-0 | W3 | 3 |
| 4/4/2021 | | @ | Oak | L | | 6 | 15 | 3 | 1 | .750 | 3-1 | L1 | 4 |
| 4/5/2021 | | @ | LAA | W | Correa, C | 11 | 7 | 4 | 1 | .800 | 4-1 | W1 | 5 |
| 4/6/2021 | | @ | LAA | W | Tucker, K | 7 | 3 | 5 | 1 | .833 | 5-1 | W2 | 6 |
| 4/8/2021 | | | Oak | W | Alvarez, Y | 6 | 2 | 6 | 1 | .857 | 6-1 | W3 | 7 |
| 4/9/2021 | | | Oak | W | Tucker, K | 4 | 2 | 7 | 1 | .875 | 7-1 | W4 | 8 |
| 4/10/2021 | | | Oak | W | Altuve, J | 12 | 3 | 8 | 1 | .889 | 8-1 | W5 | 9 |
| 4/12/2021 | | | Det | W | | 6 | 5 | 9 | 1 | .900 | 9-1 | W6 | 10 |
| 4/13/2021 | | | Det | W | | 7 | 4 | 10 | 1 | .909 | 9-1 | W7 | 11 |
| 4/14/2021 | | | Det | W | Gurriel, Y | 8 | 4 | 11 | 1 | .917 | 9-1 | W8 | 12 |
| 4/16/2021 | | @ | Sea | W | Correa, C | 2 | 1 | 12 | 1 | .923 | 9-1 | W9 | 13 |
| 4/17/2021 | | @ | Sea | W | Correa, C | 9 | 3 | 13 | 1 | .929 | 10-0 | W10 | 14 |
| 4/18/2021 | | @ | Sea | W | Castro, J | 3 | 1 | 14 | 1 | .933 | 10-0 | W11 | 15 |
| 4/20/2021 | | @ | Col | L | | 4 | 5 | 14 | 2 | .875 | 9-1 | L1 | 16 |
| 4/21/2021 | | @ | Col | L | | 2 | 6 | 14 | 3 | .824 | 8-2 | L2 | 17 |
| 4/22/2021 | | | LAA | W | Correa, C | 5 | 0 | 15 | 3 | .833 | 8-2 | W1 | 18 |
| 4/23/2021 | | | LAA | L | | 0 | 1 | 15 | 4 | .789 | 7-3 | L1 | 19 |
| 4/24/2021 | | | LAA | W | Correa, C | 12 | 3 | 16 | 4 | .800 | 7-3 | W1 | 20 |
| 4/25/2021 | | | LAA | W | Gurriel, Y | 2 | 0 | 17 | 4 | .810 | 7-3 | W2 | 21 |
| 4/26/2021 | | | Sea | L | | 2 | 5 | 17 | 5 | .773 | 6-4 | L1 | 22 |
| 4/27/2021 | | | Sea | W | Brantley, M | 7 | 4 | 18 | 5 | .783 | 6-4 | W1 | 23 |
| 4/28/2021 | | | Sea | W | Bregman, A | 7 | 3 | 19 | 5 | .792 | 6-4 | W2 | 24 |
| 4/29/2021 | | | Sea | W | McCormick, C | 6 | 1 | 20 | 5 | .800 | 6-4 | W3 | 25 |
| 4/30/2021 | | @ | Tam | W | Tucker, K | 9 | 2 | 21 | 5 | .808 | 7-3 | W4 | 26 |
| 5/1/2021 | | @ | Tam | W | Alvarez, Y | 9 | 3 | 22 | 5 | .815 | 8-2 | W5 | 27 |
| 5/2/2021 | | @ | Tam | L | | 1 | 2 | 22 | 6 | .786 | 7-3 | L1 | 28 |
| 5/4/2021 | | @ | NYA | L | | 3 | 4 | 22 | 7 | .759 | 7-3 | L2 | 29 |
| 5/5/2021 | | @ | NYA | W | Straw, M | 6 | 5 | 23 | 7 | .767 | 7-3 | W1 | 30 |
| 5/6/2021 | | @ | NYA | W | Gurriel, Y | 5 | 1 | 24 | 7 | .774 | 7-3 | W2 | 31 |
| 5/7/2021 | | | Tor | W | Alvarez, Y | 3 | 2 | 25 | 7 | .781 | 8-2 | W3 | 32 |
| 5/8/2021 | | | Tor | L | | 3 | 7 | 25 | 8 | .758 | 7-3 | L1 | 33 |
| 5/9/2021 | | | Tor | W | Brantley, M | 5 | 4 | 26 | 8 | .765 | 7-3 | W1 | 34 |
| 5/10/2021 | | | LAA | W | Correa, C | 11 | 5 | 27 | 8 | .771 | 7-3 | W2 | 35 |
| 5/11/2021 | | | LAA | W | Correa, C | 7 | 2 | 28 | 8 | .778 | 7-3 | W3 | 36 |
| 5/12/2021 | | | LAA | W | McCormick, C | 13 | 9 | 29 | 8 | .784 | 7-3 | W4 | 37 |
| 5/13/2021 | | | Tex | L | | 2 | 4 | 29 | 9 | .763 | 7-3 | L1 | 38 |
| 5/14/2021 | | | Tex | L | | 2 | 5 | 29 | 10 | .744 | 7-3 | L2 | 39 |
| 5/15/2021 | | | Tex | W | Gurriel, Y | 9 | 2 | 30 | 10 | .750 | 7-3 | W1 | 40 |
| 5/16/2021 | | | Tex | W | Correa, C | 8 | 0 | 31 | 10 | .756 | 7-3 | W2 | 41 |
| 5/18/2021 | | @ | Oak | W | Correa, C | 6 | 1 | 32 | 10 | .762 | 7-3 | W3 | 42 |
| 5/19/2021 | | @ | Oak | W | Gurriel, Y | 9 | 2 | 33 | 10 | .767 | 8-2 | W4 | 43 |
| 5/20/2021 | | @ | Oak | L | | 2 | 6 | 33 | 11 | .750 | 7-3 | L1 | 44 |
| 5/21/2021 | | @ | Tex | L | | 8 | 17 | 33 | 12 | .733 | 6-4 | L2 | 45 |
| 5/22/2021 | | @ | Tex | W | Correa, C | 10 | 0 | 34 | 12 | .739 | 6-4 | W1 | 46 |
| 5/23/2021 | | @ | Tex | W | Bregman, A | 6 | 3 | 35 | 12 | .745 | 6-4 | W2 | 47 |
| 5/25/2021 | | | LAN | L | | 1 | 2 | 35 | 13 | .729 | 6-4 | L1 | 48 |
| 5/26/2021 | | | LAN | L | | 2 | 10 | 35 | 14 | .714 | 6-4 | L2 | 49 |
| 5/28/2021 | | | SD | W | | 10 | 5 | 36 | 14 | .720 | 6-4 | W1 | 50 |
| 5/29/2021 | | | SD | W | | 7 | 6 | 37 | 14 | .725 | 6-4 | W2 | 51 |
| 5/30/2021 | | | SD | W | Jones, T | 8 | 5 | 38 | 14 | .731 | 6-4 | W3 | 52 |
| 5/31/2021 | | | Bos | L | | 2 | 9 | 38 | 15 | .717 | 5-5 | L1 | 53 |
| 6/1/2021 | | | Bos | W | Alvarez, Y | 6 | 1 | 39 | 15 | .722 | 6-4 | W1 | 54 |
| 6/2/2021 | | | Bos | W | Straw, M | 4 | 1 | 40 | 15 | .727 | 7-3 | W2 | 55 |
| 6/3/2021 | | | Bos | L | | 0 | 4 | 40 | 16 | .714 | 6-4 | L1 | 56 |
| 6/4/2021 | | @ | Tor | W | Altuve, J | 5 | 4 | 41 | 16 | .719 | 6-4 | W1 | 57 |
| 6/5/2021 | | @ | Tor | W | Altuve, J | 11 | 7 | 42 | 16 | .724 | 7-3 | W2 | 58 |
| 6/6/2021 | | @ | Tor | L | | 6 | 11 | 42 | 17 | .712 | 7-3 | L1 | 59 |
| 6/8/2021 | | @ | Bos | W | Gurriel, Y | 8 | 3 | 43 | 17 | .717 | 7-3 | W1 | 60 |
| 6/9/2021 | | @ | Bos | L | | 5 | 7 | 43 | 18 | .705 | 6-4 | L1 | 61 |
| 6/10/2021 | | @ | Bos | W | Alvarez, Y | 4 | 2 | 44 | 18 | .710 | 6-4 | W1 | 62 |
| 6/11/2021 | | @ | Min | W | Brantley, M | 10 | 4 | 45 | 18 | .714 | 7-3 | W2 | 63 |
| 6/12/2021 | | @ | Min | W | Altuve, J | 5 | 3 | 46 | 18 | .719 | 7-3 | W3 | 64 |
| 6/13/2021 | | @ | Min | L | | 6 | 7 | 46 | 19 | .708 | 6-4 | L1 | 65 |
| 6/15/2021 | | | Tex | L | | 1 | 8 | 46 | 20 | .697 | 6-4 | L2 | 66 |
| 6/16/2021 | | | Tex | L | | 3 | 10 | 46 | 21 | .687 | 5-5 | L3 | 67 |
| 6/17/2021 | | | ChA | W | Castro, J | 6 | 5 | 47 | 21 | .691 | 5-5 | W1 | 68 |
| 6/18/2021 | | | ChA | W | Brantley, M | 4 | 1 | 48 | 21 | .696 | 6-4 | W2 | 69 |
| 6/19/2021 | | | ChA | W | Altuve, J | 12 | 2 | 49 | 21 | .700 | 6-4 | W3 | 70 |
| 6/20/2021 | | | ChA | W | Brantley, M | 4 | 3 | 50 | 21 | .704 | 7-3 | W4 | 71 |
| 6/21/2021 | | @ | Bal | W | Alvarez, Y | 7 | 4 | 51 | 21 | .708 | 7-3 | W5 | 72 |
| 6/22/2021 | | @ | Bal | L | | 2 | 5 | 51 | 22 | .699 | 6-4 | L1 | 73 |
| 6/23/2021 | | @ | Bal | W | Toro, A | 8 | 0 | 52 | 22 | .703 | 6-4 | W1 | 74 |
| 6/24/2021 | | @ | Det | L | | 4 | 9 | 52 | 23 | .693 | 6-4 | L1 | 75 |
| 6/26/2021 | 1 | @ | Det | W | Correa, C | 1 | 0 | 53 | 23 | .697 | 7-3 | W1 | 76 |
| 6/26/2021 | 2 | @ | Det | W | Alvarez, Y | 10 | 2 | 54 | 23 | .701 | 8-2 | W2 | 77 |
| 6/27/2021 | | @ | Det | L | | 2 | 9 | 54 | 24 | .692 | 7-3 | L1 | 78 |
| 6/28/2021 | | | Bal | W | Alvarez, Y | 11 | 3 | 55 | 24 | .696 | 7-3 | W1 | 79 |
| 6/29/2021 | | | Bal | W | | 10 | 0 | 56 | 24 | .700 | 7-3 | W2 | 80 |
| 6/30/2021 | | | Bal | L | | 10 | 12 | 56 | 25 | .691 | 6-4 | L1 | 81 |
| 7/1/2021 | | @ | Cle | W | Altuve, J | 3 | 2 | 57 | 25 | .695 | 6-4 | W1 | 82 |
| 7/2/2021 | | @ | Cle | W | McCormick, C | 9 | 3 | 58 | 25 | .699 | 7-3 | W2 | 83 |
| 7/3/2021 | | @ | Cle | L | | 1 | 6 | 58 | 26 | .690 | 6-4 | L1 | 84 |
| 7/4/2021 | | @ | Cle | L | | 1 | 3 | 58 | 27 | .682 | 6-4 | L2 | 85 |
| 7/6/2021 | | | Oak | L | | 3 | 6 | 58 | 28 | .674 | 5-5 | L3 | 86 |
| 7/7/2021 | | | Oak | L | | 1 | 4 | 58 | 29 | .667 | 4-6 | L4 | 87 |
| 7/8/2021 | | | Oak | W | Maldonado, M | 10 | 3 | 59 | 29 | .670 | 5-5 | W1 | 88 |
| 7/9/2021 | | | NYA | L | | 4 | 6 | 59 | 30 | .663 | 4-6 | L1 | 89 |
| 7/10/2021 | | | NYA | W | Straw, M | 5 | 3 | 60 | 30 | .667 | 4-6 | W1 | 90 |
| 7/11/2021 | | | NYA | W | Alvarez, Y | 3 | 2 | 61 | 30 | .670 | 5-5 | W2 | 91 |
| 7/16/2021 | | @ | ChA | L | | 2 | 4 | 61 | 31 | .663 | 4-6 | L1 | 92 |
| 7/17/2021 | | @ | ChA | W | Alvarez, Y | 6 | 0 | 62 | 31 | .667 | 4-6 | W1 | 93 |
| 7/18/2021 | | @ | ChA | L | | 0 | 2 | 62 | 32 | .660 | 4-6 | L1 | 94 |
| 7/19/2021 | | | Cle | L | | 2 | 3 | 62 | 33 | .653 | 4-6 | L2 | 95 |
| 7/20/2021 | | | Cle | W | Tucker, K | 3 | 2 | 63 | 33 | .656 | 5-5 | W1 | 96 |
| 7/21/2021 | | | Cle | L | | 0 | 3 | 63 | 34 | .649 | 5-5 | L1 | 97 |
| 7/23/2021 | | | Tex | W | Correa, C | 4 | 3 | 64 | 34 | .653 | 5-5 | W1 | 98 |
| 7/24/2021 | | | Tex | L | | 0 | 2 | 64 | 35 | .646 | 5-5 | L1 | 99 |
| 7/25/2021 | | | Tex | L | | 4 | 6 | 64 | 36 | .640 | 4-6 | L2 | 100 |
| 7/26/2021 | | @ | Sea | W | Gurriel, Y | 9 | 7 | 65 | 36 | .644 | 4-6 | W1 | 101 |
| 7/27/2021 | | @ | Sea | W | Straw, M | 15 | 8 | 66 | 36 | .647 | 5-5 | W2 | 102 |
| 7/28/2021 | | @ | Sea | W | Alvarez, Y | 4 | 1 | 67 | 36 | .650 | 5-5 | W3 | 103 |
| 7/30/2021 | | @ | SF | W | Correa, C | 6 | 5 | 68 | 36 | .654 | 6-4 | W4 | 104 |
| 7/31/2021 | | @ | SF | L | | 0 | 7 | 68 | 37 | .648 | 6-4 | L1 | 105 |
| 8/1/2021 | | @ | SF | L | | 3 | 5 | 68 | 38 | .642 | 5-5 | L2 | 106 |
| 8/3/2021 | | @ | LAN | L | | 5 | 6 | 68 | 39 | .636 | 5-5 | L3 | 107 |
| 8/4/2021 | | @ | LAN | L | | 2 | 3 | 68 | 40 | .630 | 4-6 | L4 | 108 |
| 8/5/2021 | | | Min | L | | 2 | 5 | 68 | 41 | .624 | 4-6 | L5 | 109 |
| 8/6/2021 | | | Min | L | | 3 | 7 | 68 | 42 | .618 | 4-6 | L6 | 110 |
| 8/7/2021 | | | Min | W | Tucker, K | 6 | 2 | 69 | 42 | .622 | 4-6 | W1 | 111 |
| 8/8/2021 | | | Min | L | | 4 | 7 | 69 | 43 | .616 | 3-7 | L1 | 112 |
| 8/10/2021 | | | Col | W | Tucker, K | 3 | 2 | 70 | 43 | .619 | 3-7 | W1 | 113 |
| 8/11/2021 | | | Col | W | Meyers, J | 4 | 1 | 71 | 43 | .623 | 3-7 | W2 | 114 |
| 8/13/2021 | | @ | LAA | L | | 2 | 3 | 71 | 44 | .617 | 3-7 | L1 | 115 |
| 8/14/2021 | | @ | LAA | W | Correa, C | 7 | 2 | 72 | 44 | .621 | 4-6 | W1 | 116 |
| 8/15/2021 | | @ | LAA | W | McCormick, C | 15 | 3 | 73 | 44 | .624 | 5-5 | W2 | 117 |
| 8/16/2021 | | @ | KC | L | | 0 | 2 | 73 | 45 | .619 | 5-5 | L1 | 118 |
| 8/17/2021 | | @ | KC | W | | 4 | 2 | 74 | 45 | .622 | 6-4 | W1 | 119 |
| 8/18/2021 | | @ | KC | W | Brantley, M | 8 | 5 | 75 | 45 | .625 | 7-3 | W2 | 120 |
| 8/19/2021 | | @ | KC | L | | 5 | 12 | 75 | 46 | .620 | 6-4 | L1 | 121 |
| 8/20/2021 | | | Sea | W | Altuve, J | 4 | 0 | 76 | 46 | .623 | 7-3 | W1 | 122 |
| 8/21/2021 | | | Sea | L | | 2 | 10 | 76 | 47 | .618 | 6-4 | L1 | 123 |
| 8/22/2021 | | | Sea | L | | 2 | 12 | 76 | 48 | .613 | 5-5 | L2 | 124 |
| 8/23/2021 | | | KC | L | | 5 | 7 | 76 | 49 | .608 | 5-5 | L3 | 125 |
| 8/24/2021 | | | KC | L | | 1 | 3 | 76 | 50 | .603 | 4-6 | L4 | 126 |
| 8/25/2021 | | | KC | W | Alvarez, Y | 4 | 2 | 77 | 50 | .606 | 4-6 | W1 | 127 |
| 8/27/2021 | | @ | Tex | W | Gurriel, Y | 7 | 3 | 78 | 50 | .609 | 5-5 | W2 | 128 |
| 8/28/2021 | | @ | Tex | L | | 2 | 3 | 78 | 51 | .605 | 4-6 | L1 | 129 |
| 8/29/2021 | | @ | Tex | W | Meyers, J | 5 | 3 | 79 | 51 | .608 | 4-6 | W1 | 130 |
| 8/30/2021 | | @ | Sea | L | | 2 | 3 | 79 | 52 | .603 | 4-6 | L1 | 131 |
| 8/31/2021 | | @ | Sea | W | Bregman, A | 6 | 0 | 80 | 52 | .606 | 4-6 | W1 | 132 |
| 9/1/2021 | | @ | Sea | W | Alvarez, Y | 10 | 1 | 81 | 52 | .609 | 5-5 | W2 | 133 |
| 9/3/2021 | | @ | SD | W | McCormick, C | 7 | 4 | 82 | 52 | .612 | 6-4 | W3 | 134 |
| 9/4/2021 | | @ | SD | L | | 0 | 7 | 82 | 53 | .607 | 6-4 | L1 | 135 |
| 9/5/2021 | | @ | SD | L | | 0 | 6 | 82 | 54 | .603 | 6-4 | L2 | 136 |
| 9/6/2021 | | | Sea | L | | 3 | 4 | 82 | 55 | .599 | 5-5 | L3 | 137 |
| 9/7/2021 | | | Sea | W | Alvarez, Y | 7 | 6 | 83 | 55 | .601 | 5-5 | W1 | 138 |
| 9/8/2021 | | | Sea | W | Brantley, M | 12 | 4 | 84 | 55 | .604 | 6-4 | W2 | 139 |
| 9/10/2021 | | | LAA | W | Alvarez, Y | 4 | 3 | 85 | 55 | .607 | 6-4 | W3 | 140 |
| 9/11/2021 | | | LAA | W | Alvarez, Y | 3 | 2 | 86 | 55 | .610 | 7-3 | W4 | 141 |
| 9/12/2021 | | | LAA | W | Maldonado, M | 4 | 2 | 87 | 55 | .613 | 7-3 | W5 | 142 |
| 9/13/2021 | | @ | Tex | L | | 3 | 4 | 87 | 56 | .608 | 6-4 | L1 | 143 |
| 9/14/2021 | | @ | Tex | L | | 1 | 4 | 87 | 57 | .604 | 5-5 | L2 | 144 |
| 9/15/2021 | | @ | Tex | W | Alvarez, Y | 10 | 3 | 88 | 57 | .607 | 6-4 | W1 | 145 |
| 9/16/2021 | | @ | Tex | L | | 4 | 6 | 88 | 58 | .603 | 6-4 | L1 | 146 |
| 9/17/2021 | | | Ari | W | Bregman, A | 8 | 6 | 89 | 58 | .605 | 7-3 | W1 | 147 |
| 9/18/2021 | | | Ari | L | | 3 | 4 | 89 | 59 | .601 | 6-4 | L1 | 148 |
| 9/19/2021 | | | Ari | L | | 5 | 8 | 89 | 60 | .597 | 5-5 | L2 | 149 |
| 9/20/2021 | | @ | LAA | W | Gonzalez, M | 9 | 4 | 90 | 60 | .600 | 5-5 | W1 | 150 |
| 9/21/2021 | | @ | LAA | W | Gurriel, Y | 7 | 6 | 91 | 60 | .603 | 5-5 | W2 | 151 |
| 9/22/2021 | | @ | LAA | W | Alvarez, Y | 9 | 7 | 92 | 60 | .605 | 5-5 | W3 | 152 |
| 9/23/2021 | | @ | LAA | L | | 2 | 4 | 92 | 61 | .601 | 5-5 | L1 | 153 |
| 9/24/2021 | | @ | Oak | L | | 1 | 2 | 92 | 62 | .597 | 5-5 | L2 | 154 |
| 9/25/2021 | | @ | Oak | W | Tucker, K | 3 | 0 | 93 | 62 | .600 | 5-5 | W1 | 155 |
| 9/26/2021 | | @ | Oak | W | Altuve, J | 4 | 1 | 94 | 62 | .603 | 6-4 | W2 | 156 |
| 9/28/2021 | | | Tam | L | | 2 | 8 | 94 | 63 | .599 | 5-5 | L1 | 157 |
| 9/29/2021 | | | Tam | L | | 1 | 6 | 94 | 64 | .595 | 5-5 | L2 | 158 |
| 9/30/2021 | | | Tam | L | | 2 | 5 | 94 | 65 | .591 | 5-5 | L3 | 159 |
| 10/1/2021 | | | Oak | L | | 4 | 5 | 94 | 66 | .587 | 4-6 | L4 | 160 |
| 10/2/2021 | | | Oak | L | | 6 | 11 | 94 | 67 | .584 | 3-7 | L5 | 161 |
| 10/3/2021 | | | Oak | W | Maldonado, M | 5 | 4 | 95 | 67 | .586 | 3-7 | W1 | 162 |