Team game results - 2021 Chicago (A)
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 10/4/2005 | 1 | @ | Bos | W | 6-2 | | | R | | | | R |
| 4/1/2021 | | @ | LAA | W | 5-3 | | Giolito, L | R | Giolito, L | Hendriks, L | Bundy, D | R |
| 4/2/2021 | | @ | LAA | L | 2-4 | | Keuchel, D | L | Keuchel, D | | Heaney, A | L |
| 4/3/2021 | | @ | LAA | W | 5-1 | | Lynn, L | R | Lynn, L | | Cobb, A | R |
| 4/4/2021 | | @ | LAA | W | 4-2 | | Cease, D | R | Cease, D | Hendriks, L | Ohtani, S | R |
| 4/5/2021 | | @ | Sea | W | 6-1 | | Rodon, C | L | Rodon, C | Kopech, M | Sheffield, J | L |
| 4/6/2021 | | @ | Sea | L | 3-4 | | Giolito, L | R | Giolito, L | | Paxton, J | L |
| 4/7/2021 | | @ | Sea | W | 4-3 | | Keuchel, D | L | Keuchel, D | Hendriks, L | Dunn, J | R |
| 4/8/2021 | | | KC | L | 1-4 | | Lynn, L | R | Crochet, G | | Keller, B | R |
| 4/11/2021 | | | KC | W | 3-2 | | Cease, D | R | Bummer, A | | Minor, M | L |
| 4/12/2021 | | | Cle | W | 12-5 | | Keuchel, D | L | Crochet, G | | McKenzie, T | R |
| 4/13/2021 | | | Cle | L | 1-2 | | Giolito, L | R | Giolito, L | | Bieber, S | R |
| 4/14/2021 | | | Cle | W | 10-3 | | Rodon, C | L | Rodon, C | | Plesac, Z | R |
| 4/15/2021 | | | Cle | L | 0-2 | | Lynn, L | R | Lynn, L | | Civale, A | R |
| 4/17/2021 | | @ | Bos | W | 3-1 | | Cease, D | R | Cease, D | Hendriks, L | Pivetta, N | R |
| 4/18/2021 | 1 | @ | Bos | L | 3-4 | 7 | Keuchel, D | L | Marshall, E | | Houck, T | R |
| 4/18/2021 | 2 | @ | Bos | W | 3-2 | 7 | Kopech, M | R | Kopech, M | Hendriks, L | Perez, M | L |
| 4/19/2021 | | @ | Bos | W | 3-2 | | Giolito, L | R | Giolito, L | Hendriks, L | Eovaldi, N | R |
| 4/20/2021 | | @ | Cle | W | 7-2 | | Rodon, C | L | Rodon, C | | Plesac, Z | R |
| 4/23/2021 | | | Tex | W | 8-4 | | Cease, D | R | Cease, D | Hendriks, L | Dunning, D | R |
| 4/24/2021 | | | Tex | L | 0-2 | | Keuchel, D | L | Keuchel, D | | Gibson, K | R |
| 4/25/2021 | | | Tex | W | 3-2 | | Kopech, M | R | Crochet, G | Hendriks, L | Arihara, K | R |
| 4/27/2021 | | | Det | W | 9-5 | | Giolito, L | R | Ruiz, J | | Urena, J | R |
| 4/29/2021 | 1 | | Det | W | 2-0 | 7 | Rodon, C | L | Rodon, C | | Mize, C | R |
| 4/29/2021 | 2 | | Det | W | 13-4 | 7 | Cease, D | R | Marshall, E | | Boyd, M | L |
| 4/30/2021 | | | Cle | L | 3-9 | | Keuchel, D | L | Keuchel, D | | Bieber, S | R |
| 5/1/2021 | | | Cle | W | 7-2 | | Lynn, L | R | Lynn, L | | McKenzie, T | R |
| 5/2/2021 | | | Cle | L | 1-4 | | Giolito, L | R | Giolito, L | | Plesac, Z | R |
| 5/4/2021 | | @ | Cin | L | 5-9 | | Cease, D | R | Cease, D | | Hoffman, J | R |
| 5/5/2021 | | @ | Cin | L | 4-5 | | Keuchel, D | L | Kopech, M | | Gray, S | R |
| 5/7/2021 | | @ | KC | W | 3-0 | | Rodon, C | L | Rodon, C | Hendriks, L | Keller, B | R |
| 5/8/2021 | | @ | KC | W | 12-8 | | Lynn, L | R | Lynn, L | | Lynch, D | L |
| 5/9/2021 | | @ | KC | L | 4-5 | | Giolito, L | R | Kopech, M | | Minor, M | L |
| 5/11/2021 | | | Min | W | 9-2 | | Cease, D | R | Cease, D | | Maeda, K | R |
| 5/12/2021 | | | Min | W | 14-6 | | Keuchel, D | L | Keuchel, D | | Happ, J | L |
| 5/13/2021 | | | Min | L | 4-15 | | Lynn, L | R | Lynn, L | | Pineda, M | R |
| 5/14/2021 | 1 | | KC | W | 9-2 | 7 | Giolito, L | R | Giolito, L | | Keller, B | R |
| 5/14/2021 | 2 | | KC | W | 4-0 | 7 | Kopech, M | R | Kopech, M | | Junis, J | R |
| 5/15/2021 | | | KC | W | 3-0 | | Rodon, C | L | Rodon, C | Hendriks, L | Minor, M | L |
| 5/16/2021 | | | KC | W | 3-1 | | Cease, D | R | Marshall, E | Ruiz, J | Singer, B | R |
| 5/17/2021 | | @ | Min | W | 9-1 | | Keuchel, D | L | Keuchel, D | | Happ, J | L |
| 5/18/2021 | | @ | Min | W | 4-3 | | Lynn, L | R | Lynn, L | Hendriks, L | Ober, B | R |
| 5/19/2021 | | @ | Min | W | 3-2 | | Giolito, L | R | Kopech, M | Hendriks, L | Shoemaker, M | R |
| 5/21/2021 | | @ | NYA | L | 3-7 | | Rodon, C | L | Rodon, C | | Montgomery, J | L |
| 5/22/2021 | | @ | NYA | W | 4-2 | 11 | Cease, D | R | Hendriks, L | | Cole, G | R |
| 5/23/2021 | | @ | NYA | W | 8-7 | | Keuchel, D | L | Foster, M | Hendriks, L | Taillon, J | R |
| 5/24/2021 | | | StL | W | 10-2 | | Lynn, L | R | Lynn, L | | Kim, K | L |
| 5/25/2021 | | | StL | L | 0-1 | | Giolito, L | R | Giolito, L | | Flaherty, J | R |
| 5/26/2021 | | | StL | W | 4-1 | | Rodon, C | L | Rodon, C | Bummer, A | Gant, J | R |
| 5/27/2021 | | | Bal | W | 2-0 | | Cease, D | R | Cease, D | Hendriks, L | Zimmermann, B | L |
| 5/29/2021 | 1 | | Bal | W | 5-4 | 7 | Keuchel, D | L | Ruiz, J | Hendriks, L | Harvey, M | R |
| 5/29/2021 | 2 | | Bal | W | 1-0 | 7 | Lynn, L | R | Lynn, L | | Means, J | L |
| 5/30/2021 | | | Bal | W | 24-0 | | Giolito, L | R | Giolito, L | | Akin, K | L |
| 5/31/2021 | 1 | @ | Cle | W | 5-0 | 7 | Rodon, C | L | Rodon, C | | McKenzie, T | R |
| 5/31/2021 | 2 | @ | Cle | L | 0-1 | 7 | Lambert, J | R | Lambert, J | | Quantrill, C | R |
| 6/1/2021 | | @ | Cle | L | 5-10 | | Cease, D | R | Cease, D | | Bieber, S | R |
| 6/3/2021 | | | Det | W | 4-1 | | Lynn, L | R | Lynn, L | Hendriks, L | Mize, C | R |
| 6/4/2021 | | | Det | L | 4-7 | | Keuchel, D | L | Keuchel, D | | Turnbull, S | R |
| 6/5/2021 | | | Det | W | 12-2 | | Giolito, L | R | Giolito, L | | Skubal, T | L |
| 6/6/2021 | | | Det | L | 2-9 | | Cease, D | R | Cease, D | | Urena, J | R |
| 6/8/2021 | | | Tor | L | 5-6 | | Rodon, C | L | Hendriks, L | | Ray, R | L |
| 6/9/2021 | | | Tor | L | 4-6 | | Lynn, L | R | Lynn, L | | Manoah, A | R |
| 6/10/2021 | | | Tor | L | 7-17 | | Keuchel, D | L | Keuchel, D | | Ryu, H | L |
| 6/11/2021 | | @ | Det | L | 3-4 | | Giolito, L | R | Giolito, L | | Skubal, T | L |
| 6/12/2021 | | @ | Det | W | 1-0 | | Cease, D | R | Cease, D | Foster, M | Urena, J | R |
| 6/13/2021 | | @ | Det | W | 7-1 | | Rodon, C | L | Rodon, C | | Funkhouser, K | R |
| 6/14/2021 | | | Tam | L | 3-6 | | Lynn, L | R | Lynn, L | | Glasnow, T | R |
| 6/15/2021 | | | Tam | L | 3-7 | | Keuchel, D | L | Keuchel, D | | McClanahan, S | L |
| 6/16/2021 | | | Tam | W | 13-1 | | Giolito, L | R | Giolito, L | | Yarbrough, R | L |
| 6/17/2021 | | @ | Hou | L | 5-6 | | Cease, D | R | Foster, M | | Urquidy, J | R |
| 6/18/2021 | | @ | Hou | L | 1-4 | | Rodon, C | L | Rodon, C | | Garcia, L | R |
| 6/19/2021 | | @ | Hou | L | 2-12 | | Lynn, L | R | Lynn, L | | Valdez, F | L |
| 6/20/2021 | | @ | Hou | L | 3-4 | | Keuchel, D | L | Bummer, A | | McCullers, L | R |
| 6/22/2021 | | @ | Pit | L | 4-6 | | Giolito, L | R | Ruiz, J | | Anderson, T | L |
| 6/23/2021 | | @ | Pit | W | 7-6 | | Cease, D | R | Cease, D | Hendriks, L | De Jong, C | R |
| 6/25/2021 | | | Sea | L | 2-5 | | Rodon, C | L | Rodon, C | | Kikuchi, Y | L |
| 6/26/2021 | | | Sea | W | 12-4 | | Lynn, L | R | Lynn, L | | Gilbert, L | R |
| 6/27/2021 | | | Sea | L | 7-10 | 7 | Burr, R | R | Hendriks, L | | Dugger, R | R |
| 6/29/2021 | | | Min | W | 4-2 | | Giolito, L | R | Giolito, L | Hendriks, L | Maeda, K | R |
| 6/30/2021 | | | Min | W | 2-1 | | Cease, D | R | Crochet, G | Kopech, M | Ober, B | R |
| 7/1/2021 | | | Min | W | 2-1 | 10 | Rodon, C | L | Ruiz, J | | Berrios, J | R |
| 7/2/2021 | | @ | Det | L | 3-4 | | Lynn, L | R | Kopech, M | | Mize, C | R |
| 7/3/2021 | | @ | Det | L | 2-5 | | Keuchel, D | L | Keuchel, D | | Skubal, T | L |
| 7/4/2021 | | @ | Det | L | 4-5 | 10 | Giolito, L | R | Crochet, G | | Manning, M | R |
| 7/5/2021 | | @ | Min | L | 4-5 | 10 | Cease, D | R | Kopech, M | | Ober, B | R |
| 7/6/2021 | | @ | Min | W | 2-1 | 11 | Rodon, C | L | Hendriks, L | Foster, M | Berrios, J | R |
| 7/7/2021 | | @ | Min | W | 9-8 | | Lynn, L | R | Ruiz, J | | Pineda, M | R |
| 7/9/2021 | | @ | Bal | W | 13-4 | | Keuchel, D | L | Keuchel, D | | Lopez, J | R |
| 7/10/2021 | | @ | Bal | W | 9-5 | | Giolito, L | R | Giolito, L | | Eshelman, T | R |
| 7/11/2021 | | @ | Bal | L | 2-4 | | Cease, D | R | Cease, D | | Watkins, S | R |
| 7/16/2021 | | | Hou | W | 4-2 | | Cease, D | R | Cease, D | Hendriks, L | McCullers, L | R |
| 7/17/2021 | | | Hou | L | 0-6 | | Giolito, L | R | Giolito, L | | Odorizzi, J | R |
| 7/18/2021 | | | Hou | W | 2-0 | | Rodon, C | L | Rodon, C | Hendriks, L | Valdez, F | L |
| 7/19/2021 | 1 | | Min | W | 6-5 | 7 | Lynn, L | R | Ruiz, J | Hendriks, L | Jax, G | R |
| 7/19/2021 | 2 | | Min | W | 2-0 | 7 | Lopez, R | R | Lopez, R | Foster, M | Berrios, J | R |
| 7/20/2021 | | | Min | L | 0-4 | | Keuchel, D | L | Keuchel, D | | Ober, B | R |
| 7/21/2021 | | | Min | W | 6-5 | | Cease, D | R | Cease, D | Hendriks, L | Pineda, M | R |
| 7/23/2021 | | @ | Mil | L | 2-7 | | Giolito, L | R | Giolito, L | | Peralta, F | R |
| 7/24/2021 | | @ | Mil | L | 1-4 | | Rodon, C | L | Rodon, C | | Burnes, C | R |
| 7/25/2021 | | @ | Mil | L | 5-8 | | Lynn, L | R | Lynn, L | | Woodruff, B | R |
| 7/26/2021 | | @ | KC | W | 10-6 | | Keuchel, D | L | Keuchel, D | | Minor, M | L |
| 7/27/2021 | | @ | KC | L | 2-5 | | Cease, D | R | Cease, D | | Keller, B | R |
| 7/28/2021 | | @ | KC | L | 7-8 | | Giolito, L | R | Giolito, L | | Bubic, K | L |
| 7/29/2021 | | @ | KC | W | 7-3 | | Rodon, C | L | Rodon, C | Hendriks, L | Hernandez, C | R |
| 7/30/2021 | | | Cle | L | 0-3 | | Lynn, L | R | Lynn, L | | Mejia, J | R |
| 7/31/2021 | | | Cle | L | 0-3 | | Keuchel, D | L | Keuchel, D | | McKenzie, T | R |
| 8/1/2021 | | | Cle | L | 8-12 | | Lambert, J | R | Tepera, R | | Quantrill, C | R |
| 8/3/2021 | | | KC | L | 5-10 | | Cease, D | R | Cease, D | | Bubic, K | L |
| 8/4/2021 | | | KC | W | 4-3 | | Giolito, L | R | Giolito, L | Hendriks, L | Hernandez, C | R |
| 8/5/2021 | | | KC | W | 13-10 | 10 | Keuchel, D | L | Bummer, A | | Lynch, D | L |
| 8/6/2021 | | @ | ChN | W | 4-3 | | Lynn, L | R | Kimbrel, C | Hendriks, L | Hendricks, K | R |
| 8/7/2021 | | @ | ChN | L | 5-6 | | Rodon, C | L | Ruiz, J | | Alzolay, A | R |
| 8/8/2021 | | @ | ChN | L | 2-3 | | Cease, D | R | Ruiz, J | | Davies, Z | R |
| 8/9/2021 | | @ | Min | W | 8-3 | | Giolito, L | R | Giolito, L | | Burrows, B | R |
| 8/10/2021 | | @ | Min | L | 5-7 | 10 | Keuchel, D | L | Hendriks, L | | Jax, G | R |
| 8/11/2021 | | @ | Min | W | 5-1 | | Lopez, R | R | Lopez, R | | Ober, B | R |
| 8/12/2021 | | | NYA | W | 10-4 | | Lynn, L | R | Lynn, L | | Heaney, A | L |
| 8/14/2021 | | | NYA | W | 7-4 | | Cease, D | R | Cease, D | Hendriks, L | Taillon, J | R |
| 8/15/2021 | | | NYA | L | 6-12 | | Giolito, L | R | Giolito, L | | Cortes, N | L |
| 8/16/2021 | | | Oak | L | 3-7 | | Keuchel, D | L | Keuchel, D | | Montas, F | R |
| 8/17/2021 | | | Oak | L | 1-5 | | Lopez, R | R | Lopez, R | | Bassitt, C | R |
| 8/18/2021 | | | Oak | L | 1-2 | | Lynn, L | R | Lynn, L | | Blackburn, P | R |
| 8/19/2021 | | | Oak | L | 4-8 | 10 | Cease, D | R | Hendriks, L | | Irvin, C | L |
| 8/20/2021 | | @ | Tam | W | 7-2 | | Giolito, L | R | Giolito, L | | Wacha, M | R |
| 8/21/2021 | | @ | Tam | L | 3-13 | | Keuchel, D | L | Keuchel, D | | Patino, L | R |
| 8/22/2021 | | @ | Tam | L | 2-3 | 13 | Lopez, R | R | Kopech, M | | Archer, C | R |
| 8/23/2021 | | @ | Tor | L | 2-6 | | Lynn, L | R | Tepera, R | | Manoah, A | R |
| 8/24/2021 | | @ | Tor | L | 5-6 | 10 | Cease, D | R | Kimbrel, C | | Berrios, J | R |
| 8/25/2021 | | @ | Tor | L | 3-6 | | Giolito, L | R | Giolito, L | | Ray, R | L |
| 8/26/2021 | | @ | Tor | W | 7-0 | | Rodon, C | L | Rodon, C | | Ryu, H | L |
| 8/27/2021 | | | ChN | W | 6-2 | | Keuchel, D | L | Keuchel, D | | Thompson, K | R |
| 8/28/2021 | | | ChN | W | 4-3 | | Lynn, L | R | Lynn, L | Hendriks, L | Mills, A | R |
| 8/29/2021 | | | ChN | W | 17-6 | | Cease, D | R | Crochet, G | | Hendricks, K | R |
| 8/31/2021 | | | Pit | L | 6-9 | | Giolito, L | R | Bummer, A | | Wilson, B | R |
| 9/1/2021 | | | Pit | W | 8-0 | | Rodon, C | L | Rodon, C | | Kranick, M | R |
| 9/3/2021 | | @ | KC | W | 6-0 | | Keuchel, D | L | Keuchel, D | | Hernandez, C | R |
| 9/4/2021 | | @ | KC | L | 2-3 | | Lopez, R | R | Tepera, R | | Lynch, D | L |
| 9/5/2021 | | @ | KC | L | 0-3 | | Cease, D | R | Cease, D | | Singer, B | R |
| 9/7/2021 | | @ | Oak | W | 5-1 | | Lambert, J | R | Lambert, J | | Kaprielian, J | R |
| 9/8/2021 | | @ | Oak | L | 0-10 | | Keuchel, D | L | Keuchel, D | | Montas, F | R |
| 9/9/2021 | | @ | Oak | W | 5-0 | | Lopez, R | R | Lopez, R | | Manaea, S | L |
| 9/10/2021 | | | Bos | W | 7-0 | | Rodon, C | L | Rodon, C | | Houck, T | R |
| 9/11/2021 | | | Bos | L | 4-5 | | Cease, D | R | Hendriks, L | | Seabold, C | R |
| 9/12/2021 | | | Bos | L | 0-13 | | Lynn, L | R | Lynn, L | | Pivetta, N | R |
| 9/14/2021 | | | LAA | W | 6-3 | | Giolito, L | R | Giolito, L | Hendriks, L | Naughton, P | L |
| 9/15/2021 | | | LAA | W | 10-0 | | Keuchel, D | L | Keuchel, D | | Junk, J | R |
| 9/16/2021 | | | LAA | L | 3-5 | | Lopez, R | R | Lopez, R | | Cobb, A | R |
| 9/17/2021 | | @ | Tex | W | 8-1 | | Cease, D | R | Cease, D | | Hearn, T | L |
| 9/18/2021 | | @ | Tex | W | 3-2 | | Lynn, L | R | Lynn, L | Hendriks, L | Howard, S | R |
| 9/19/2021 | | @ | Tex | L | 7-8 | | Giolito, L | R | Burr, R | | Lyles, J | R |
| 9/20/2021 | | @ | Det | L | 5-13 | | Rodon, C | L | Rodon, C | | Manning, M | R |
| 9/21/2021 | | @ | Det | W | 4-0 | | Keuchel, D | L | Keuchel, D | | Alexander, T | L |
| 9/23/2021 | 1 | @ | Cle | W | 3-2 | 7 | Lopez, R | R | Bummer, A | Hendriks, L | Civale, A | R |
| 9/23/2021 | 2 | @ | Cle | L | 0-2 | 7 | Kopech, M | R | Kopech, M | | Plesac, Z | R |
| 9/24/2021 | | @ | Cle | W | 4-2 | | Cease, D | R | Cease, D | Hendriks, L | Bieber, S | R |
| 9/25/2021 | | @ | Cle | W | 5-1 | | Lynn, L | R | Lynn, L | | Morgan, E | R |
| 9/26/2021 | | @ | Cle | L | 2-3 | | Giolito, L | R | Foster, M | | McKenzie, T | R |
| 9/27/2021 | | @ | Det | L | 0-10 | | Keuchel, D | L | Keuchel, D | | Manning, M | R |
| 9/28/2021 | | | Cin | W | 6-2 | | Lopez, R | R | Burr, R | | O'Brien, R | R |
| 9/29/2021 | | | Cin | W | 8-0 | | Rodon, C | L | Rodon, C | | Gray, S | R |
| 10/1/2021 | | | Det | W | 9-2 | | Lynn, L | R | Lynn, L | | Peralta, W | R |
| 10/2/2021 | | | Det | W | 4-3 | 11 | Giolito, L | R | Hendriks, L | | Manning, M | R |
| 10/3/2021 | | | Det | W | 7-2 | | Cease, D | R | Cease, D | | Alexander, T | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 10/4/2005 | 1 | @ | Bos | W | | 6 | 2 | 90 | 73 | .552 | 8-2 | W6 | 163 |
| 4/1/2021 | | @ | LAA | W | Collins, Z | 5 | 3 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/2/2021 | | @ | LAA | L | | 2 | 4 | 1 | 1 | .500 | 1-1 | L1 | 2 |
| 4/3/2021 | | @ | LAA | W | Abreu, J | 5 | 1 | 2 | 1 | .667 | 2-1 | W1 | 3 |
| 4/4/2021 | | @ | LAA | W | Moncada, Y | 4 | 2 | 3 | 1 | .750 | 3-1 | W2 | 4 |
| 4/5/2021 | | @ | Sea | W | Vaughn, A | 6 | 1 | 4 | 1 | .800 | 4-1 | W3 | 5 |
| 4/6/2021 | | @ | Sea | L | | 3 | 4 | 4 | 2 | .667 | 4-2 | L1 | 6 |
| 4/7/2021 | | @ | Sea | W | Abreu, J | 4 | 3 | 5 | 2 | .714 | 5-2 | W1 | 7 |
| 4/8/2021 | | | KC | L | | 1 | 4 | 5 | 3 | .625 | 5-3 | L1 | 8 |
| 4/11/2021 | | | KC | W | Moncada, Y | 3 | 2 | 6 | 3 | .667 | 6-3 | W1 | 9 |
| 4/12/2021 | | | Cle | W | Abreu, J | 12 | 5 | 7 | 3 | .700 | 7-3 | W2 | 10 |
| 4/13/2021 | | | Cle | L | | 1 | 2 | 7 | 4 | .636 | 6-4 | L1 | 11 |
| 4/14/2021 | | | Cle | W | Moncada, Y | 10 | 3 | 8 | 4 | .667 | 7-3 | W1 | 12 |
| 4/15/2021 | | | Cle | L | | 0 | 2 | 8 | 5 | .615 | 6-4 | L1 | 13 |
| 4/17/2021 | | @ | Bos | W | Vaughn, A | 3 | 1 | 9 | 5 | .643 | 6-4 | W1 | 14 |
| 4/18/2021 | 1 | @ | Bos | L | | 3 | 4 | 9 | 6 | .600 | 5-5 | L1 | 15 |
| 4/18/2021 | 2 | @ | Bos | W | Moncada, Y | 3 | 2 | 10 | 6 | .625 | 6-4 | W1 | 16 |
| 4/19/2021 | | @ | Bos | W | Grandal, Y | 3 | 2 | 11 | 6 | .647 | 6-4 | W2 | 17 |
| 4/20/2021 | | @ | Cle | W | Mercedes, Y | 7 | 2 | 12 | 6 | .667 | 7-3 | W3 | 18 |
| 4/23/2021 | | | Tex | W | Moncada, Y | 8 | 4 | 13 | 6 | .684 | 7-3 | W4 | 19 |
| 4/24/2021 | | | Tex | L | | 0 | 2 | 13 | 7 | .650 | 6-4 | L1 | 20 |
| 4/25/2021 | | | Tex | W | Robert, L | 3 | 2 | 14 | 7 | .667 | 7-3 | W1 | 21 |
| 4/27/2021 | | | Det | W | Grandal, Y | 9 | 5 | 15 | 7 | .682 | 7-3 | W2 | 22 |
| 4/29/2021 | 1 | | Det | W | Anderson, T | 2 | 0 | 16 | 7 | .696 | 8-2 | W3 | 23 |
| 4/29/2021 | 2 | | Det | W | | 13 | 4 | 17 | 7 | .708 | 8-2 | W4 | 24 |
| 4/30/2021 | | | Cle | L | | 3 | 9 | 17 | 8 | .680 | 8-2 | L1 | 25 |
| 5/1/2021 | | | Cle | W | Robert, L | 7 | 2 | 18 | 8 | .692 | 8-2 | W1 | 26 |
| 5/2/2021 | | | Cle | L | | 1 | 4 | 18 | 9 | .667 | 7-3 | L1 | 27 |
| 5/4/2021 | | @ | Cin | L | | 5 | 9 | 18 | 10 | .643 | 6-4 | L2 | 28 |
| 5/5/2021 | | @ | Cin | L | | 4 | 5 | 18 | 11 | .621 | 5-5 | L3 | 29 |
| 5/7/2021 | | @ | KC | W | Anderson, T | 3 | 0 | 19 | 11 | .633 | 6-4 | W1 | 30 |
| 5/8/2021 | | @ | KC | W | Garcia, L | 12 | 8 | 20 | 11 | .645 | 6-4 | W2 | 31 |
| 5/9/2021 | | @ | KC | L | | 4 | 5 | 20 | 12 | .625 | 5-5 | L1 | 32 |
| 5/11/2021 | | | Min | W | Moncada, Y | 9 | 2 | 21 | 12 | .636 | 5-5 | W1 | 33 |
| 5/12/2021 | | | Min | W | Grandal, Y | 14 | 6 | 22 | 12 | .647 | 5-5 | W2 | 34 |
| 5/13/2021 | | | Min | L | | 4 | 15 | 22 | 13 | .629 | 5-5 | L1 | 35 |
| 5/14/2021 | 1 | | KC | W | Mercedes, Y | 9 | 2 | 23 | 13 | .639 | 5-5 | W1 | 36 |
| 5/14/2021 | 2 | | KC | W | Hamilton, B | 4 | 0 | 24 | 13 | .649 | 6-4 | W2 | 37 |
| 5/15/2021 | | | KC | W | Madrigal, N | 3 | 0 | 25 | 13 | .658 | 7-3 | W3 | 38 |
| 5/16/2021 | | | KC | W | Vaughn, A | 3 | 1 | 26 | 13 | .667 | 8-2 | W4 | 39 |
| 5/17/2021 | | @ | Min | W | Grandal, Y | 9 | 1 | 27 | 13 | .675 | 8-2 | W5 | 40 |
| 5/18/2021 | | @ | Min | W | Anderson, T | 4 | 3 | 28 | 13 | .683 | 8-2 | W6 | 41 |
| 5/19/2021 | | @ | Min | W | Anderson, T | 3 | 2 | 29 | 13 | .690 | 9-1 | W7 | 42 |
| 5/21/2021 | | @ | NYA | L | | 3 | 7 | 29 | 14 | .674 | 8-2 | L1 | 43 |
| 5/22/2021 | | @ | NYA | W | Abreu, J | 4 | 2 | 30 | 14 | .682 | 8-2 | W1 | 44 |
| 5/23/2021 | | @ | NYA | W | Madrigal, N | 8 | 7 | 31 | 14 | .689 | 9-1 | W2 | 45 |
| 5/24/2021 | | | StL | W | Anderson, T | 10 | 2 | 32 | 14 | .696 | 9-1 | W3 | 46 |
| 5/25/2021 | | | StL | L | | 0 | 1 | 32 | 15 | .681 | 8-2 | L1 | 47 |
| 5/26/2021 | | | StL | W | Mendick, D | 4 | 1 | 33 | 15 | .688 | 8-2 | W1 | 48 |
| 5/27/2021 | | | Bal | W | Mendick, D | 2 | 0 | 34 | 15 | .694 | 8-2 | W2 | 49 |
| 5/29/2021 | 1 | | Bal | W | Garcia, L | 5 | 4 | 35 | 15 | .700 | 8-2 | W3 | 50 |
| 5/29/2021 | 2 | | Bal | W | Hamilton, B | 1 | 0 | 36 | 15 | .706 | 8-2 | W4 | 51 |
| 5/30/2021 | | | Bal | W | Madrigal, N | 24 | 0 | 37 | 15 | .712 | 8-2 | W5 | 52 |
| 5/31/2021 | 1 | @ | Cle | W | Eaton, A | 5 | 0 | 38 | 15 | .717 | 9-1 | W6 | 53 |
| 5/31/2021 | 2 | @ | Cle | L | | 0 | 1 | 38 | 16 | .704 | 8-2 | L1 | 54 |
| 6/1/2021 | | @ | Cle | L | | 5 | 10 | 38 | 17 | .691 | 7-3 | L2 | 55 |
| 6/3/2021 | | | Det | W | Mercedes, Y | 4 | 1 | 39 | 17 | .696 | 7-3 | W1 | 56 |
| 6/4/2021 | | | Det | L | | 4 | 7 | 39 | 18 | .684 | 7-3 | L1 | 57 |
| 6/5/2021 | | | Det | W | Moncada, Y | 12 | 2 | 40 | 18 | .690 | 7-3 | W1 | 58 |
| 6/6/2021 | | | Det | L | | 2 | 9 | 40 | 19 | .678 | 6-4 | L1 | 59 |
| 6/8/2021 | | | Tor | L | | 5 | 6 | 40 | 20 | .667 | 5-5 | L2 | 60 |
| 6/9/2021 | | | Tor | L | | 4 | 6 | 40 | 21 | .656 | 4-6 | L3 | 61 |
| 6/10/2021 | | | Tor | L | | 7 | 17 | 40 | 22 | .645 | 3-7 | L4 | 62 |
| 6/11/2021 | | @ | Det | L | | 3 | 4 | 40 | 23 | .635 | 2-8 | L5 | 63 |
| 6/12/2021 | | @ | Det | W | Goodwin, B | 1 | 0 | 41 | 23 | .641 | 3-7 | W1 | 64 |
| 6/13/2021 | | @ | Det | W | Abreu, J | 7 | 1 | 42 | 23 | .646 | 4-6 | W2 | 65 |
| 6/14/2021 | | | Tam | L | | 3 | 6 | 42 | 24 | .636 | 3-7 | L1 | 66 |
| 6/15/2021 | | | Tam | L | | 3 | 7 | 42 | 25 | .627 | 3-7 | L2 | 67 |
| 6/16/2021 | | | Tam | W | Vaughn, A | 13 | 1 | 43 | 25 | .632 | 3-7 | W1 | 68 |
| 6/17/2021 | | @ | Hou | L | | 5 | 6 | 43 | 26 | .623 | 3-7 | L1 | 69 |
| 6/18/2021 | | @ | Hou | L | | 1 | 4 | 43 | 27 | .614 | 3-7 | L2 | 70 |
| 6/19/2021 | | @ | Hou | L | | 2 | 12 | 43 | 28 | .606 | 3-7 | L3 | 71 |
| 6/20/2021 | | @ | Hou | L | | 3 | 4 | 43 | 29 | .597 | 3-7 | L4 | 72 |
| 6/22/2021 | | @ | Pit | L | | 4 | 6 | 43 | 30 | .589 | 3-7 | L5 | 73 |
| 6/23/2021 | | @ | Pit | W | Grandal, Y | 7 | 6 | 44 | 30 | .595 | 3-7 | W1 | 74 |
| 6/25/2021 | | | Sea | L | | 2 | 5 | 44 | 31 | .587 | 2-8 | L1 | 75 |
| 6/26/2021 | | | Sea | W | Goodwin, B | 12 | 4 | 45 | 31 | .592 | 3-7 | W1 | 76 |
| 6/27/2021 | | | Sea | L | | 7 | 10 | 45 | 32 | .584 | 3-7 | L1 | 77 |
| 6/29/2021 | | | Min | W | Abreu, J | 4 | 2 | 46 | 32 | .590 | 3-7 | W1 | 78 |
| 6/30/2021 | | | Min | W | Mercedes, Y | 2 | 1 | 47 | 32 | .595 | 4-6 | W2 | 79 |
| 7/1/2021 | | | Min | W | Sheets, G | 2 | 1 | 48 | 32 | .600 | 5-5 | W3 | 80 |
| 7/2/2021 | | @ | Det | L | | 3 | 4 | 48 | 33 | .593 | 5-5 | L1 | 81 |
| 7/3/2021 | | @ | Det | L | | 2 | 5 | 48 | 34 | .585 | 5-5 | L2 | 82 |
| 7/4/2021 | | @ | Det | L | | 4 | 5 | 48 | 35 | .578 | 5-5 | L3 | 83 |
| 7/5/2021 | | @ | Min | L | | 4 | 5 | 48 | 36 | .571 | 4-6 | L4 | 84 |
| 7/6/2021 | | @ | Min | W | Mendick, D | 2 | 1 | 49 | 36 | .576 | 5-5 | W1 | 85 |
| 7/7/2021 | | @ | Min | W | | 9 | 8 | 50 | 36 | .581 | 5-5 | W2 | 86 |
| 7/9/2021 | | @ | Bal | W | Moncada, Y | 13 | 4 | 51 | 36 | .586 | 6-4 | W3 | 87 |
| 7/10/2021 | | @ | Bal | W | Moncada, Y | 9 | 5 | 52 | 36 | .591 | 6-4 | W4 | 88 |
| 7/11/2021 | | @ | Bal | L | | 2 | 4 | 52 | 37 | .584 | 5-5 | L1 | 89 |
| 7/16/2021 | | | Hou | W | Anderson, T | 4 | 2 | 53 | 37 | .589 | 5-5 | W1 | 90 |
| 7/17/2021 | | | Hou | L | | 0 | 6 | 53 | 38 | .582 | 5-5 | L1 | 91 |
| 7/18/2021 | | | Hou | W | Moncada, Y | 2 | 0 | 54 | 38 | .587 | 6-4 | W1 | 92 |
| 7/19/2021 | 1 | | Min | W | Zavala, S | 6 | 5 | 55 | 38 | .591 | 7-3 | W2 | 93 |
| 7/19/2021 | 2 | | Min | W | Goodwin, B | 2 | 0 | 56 | 38 | .596 | 8-2 | W3 | 94 |
| 7/20/2021 | | | Min | L | | 0 | 4 | 56 | 39 | .589 | 7-3 | L1 | 95 |
| 7/21/2021 | | | Min | W | Vaughn, A | 6 | 5 | 57 | 39 | .594 | 7-3 | W1 | 96 |
| 7/23/2021 | | @ | Mil | L | | 2 | 7 | 57 | 40 | .588 | 6-4 | L1 | 97 |
| 7/24/2021 | | @ | Mil | L | | 1 | 4 | 57 | 41 | .582 | 5-5 | L2 | 98 |
| 7/25/2021 | | @ | Mil | L | | 5 | 8 | 57 | 42 | .576 | 5-5 | L3 | 99 |
| 7/26/2021 | | @ | KC | W | Moncada, Y | 10 | 6 | 58 | 42 | .580 | 5-5 | W1 | 100 |
| 7/27/2021 | | @ | KC | L | | 2 | 5 | 58 | 43 | .574 | 5-5 | L1 | 101 |
| 7/28/2021 | | @ | KC | L | | 7 | 8 | 58 | 44 | .569 | 4-6 | L2 | 102 |
| 7/29/2021 | | @ | KC | W | Vaughn, A | 7 | 3 | 59 | 44 | .573 | 4-6 | W1 | 103 |
| 7/30/2021 | | | Cle | L | | 0 | 3 | 59 | 45 | .567 | 3-7 | L1 | 104 |
| 7/31/2021 | | | Cle | L | | 0 | 3 | 59 | 46 | .562 | 3-7 | L2 | 105 |
| 8/1/2021 | | | Cle | L | | 8 | 12 | 59 | 47 | .557 | 2-8 | L3 | 106 |
| 8/3/2021 | | | KC | L | | 5 | 10 | 59 | 48 | .551 | 2-8 | L4 | 107 |
| 8/4/2021 | | | KC | W | Collins, Z | 4 | 3 | 60 | 48 | .556 | 3-7 | W1 | 108 |
| 8/5/2021 | | | KC | W | Jimenez, E | 13 | 10 | 61 | 48 | .560 | 4-6 | W2 | 109 |
| 8/6/2021 | | @ | ChN | W | Abreu, J | 4 | 3 | 62 | 48 | .564 | 4-6 | W3 | 110 |
| 8/7/2021 | | @ | ChN | L | | 5 | 6 | 62 | 49 | .559 | 4-6 | L1 | 111 |
| 8/8/2021 | | @ | ChN | L | | 2 | 3 | 62 | 50 | .554 | 4-6 | L2 | 112 |
| 8/9/2021 | | @ | Min | W | Abreu, J | 8 | 3 | 63 | 50 | .558 | 4-6 | W1 | 113 |
| 8/10/2021 | | @ | Min | L | | 5 | 7 | 63 | 51 | .553 | 4-6 | L1 | 114 |
| 8/11/2021 | | @ | Min | W | Engel, A | 5 | 1 | 64 | 51 | .557 | 5-5 | W1 | 115 |
| 8/12/2021 | | | NYA | W | Zavala, S | 10 | 4 | 65 | 51 | .560 | 6-4 | W2 | 116 |
| 8/14/2021 | | | NYA | W | Lamb, J | 7 | 4 | 66 | 51 | .564 | 7-3 | W3 | 117 |
| 8/15/2021 | | | NYA | L | | 6 | 12 | 66 | 52 | .559 | 6-4 | L1 | 118 |
| 8/16/2021 | | | Oak | L | | 3 | 7 | 66 | 53 | .555 | 5-5 | L2 | 119 |
| 8/17/2021 | | | Oak | L | | 1 | 5 | 66 | 54 | .550 | 4-6 | L3 | 120 |
| 8/18/2021 | | | Oak | L | | 1 | 2 | 66 | 55 | .545 | 4-6 | L4 | 121 |
| 8/19/2021 | | | Oak | L | | 4 | 8 | 66 | 56 | .541 | 4-6 | L5 | 122 |
| 8/20/2021 | | @ | Tam | W | Moncada, Y | 7 | 2 | 67 | 56 | .545 | 4-6 | W1 | 123 |
| 8/21/2021 | | @ | Tam | L | | 3 | 13 | 67 | 57 | .540 | 4-6 | L1 | 124 |
| 8/22/2021 | | @ | Tam | L | | 2 | 3 | 67 | 58 | .536 | 3-7 | L2 | 125 |
| 8/23/2021 | | @ | Tor | L | | 2 | 6 | 67 | 59 | .532 | 2-8 | L3 | 126 |
| 8/24/2021 | | @ | Tor | L | | 5 | 6 | 67 | 60 | .528 | 1-9 | L4 | 127 |
| 8/25/2021 | | @ | Tor | L | | 3 | 6 | 67 | 61 | .523 | 1-9 | L5 | 128 |
| 8/26/2021 | | @ | Tor | W | Abreu, J | 7 | 0 | 68 | 61 | .527 | 2-8 | W1 | 129 |
| 8/27/2021 | | | ChN | W | Abreu, J | 6 | 2 | 69 | 61 | .531 | 3-7 | W2 | 130 |
| 8/28/2021 | | | ChN | W | Anderson, T | 4 | 3 | 70 | 61 | .534 | 4-6 | W3 | 131 |
| 8/29/2021 | | | ChN | W | Abreu, J | 17 | 6 | 71 | 61 | .538 | 5-5 | W4 | 132 |
| 8/31/2021 | | | Pit | L | | 6 | 9 | 71 | 62 | .534 | 4-6 | L1 | 133 |
| 9/1/2021 | | | Pit | W | Jimenez, E | 8 | 0 | 72 | 62 | .537 | 5-5 | W1 | 134 |
| 9/3/2021 | | @ | KC | W | Jimenez, E | 6 | 0 | 73 | 62 | .541 | 6-4 | W2 | 135 |
| 9/4/2021 | | @ | KC | L | | 2 | 3 | 73 | 63 | .537 | 6-4 | L1 | 136 |
| 9/5/2021 | | @ | KC | L | | 0 | 3 | 73 | 64 | .533 | 6-4 | L2 | 137 |
| 9/7/2021 | | @ | Oak | W | Gonzalez, R | 5 | 1 | 74 | 64 | .536 | 7-3 | W1 | 138 |
| 9/8/2021 | | @ | Oak | L | | 0 | 10 | 74 | 65 | .532 | 6-4 | L1 | 139 |
| 9/9/2021 | | @ | Oak | W | Gonzalez, R | 5 | 0 | 75 | 65 | .536 | 6-4 | W1 | 140 |
| 9/10/2021 | | | Bos | W | Abreu, J | 7 | 0 | 76 | 65 | .539 | 6-4 | W2 | 141 |
| 9/11/2021 | | | Bos | L | | 4 | 5 | 76 | 66 | .535 | 5-5 | L1 | 142 |
| 9/12/2021 | | | Bos | L | | 0 | 13 | 76 | 67 | .531 | 5-5 | L2 | 143 |
| 9/14/2021 | | | LAA | W | Robert, L | 6 | 3 | 77 | 67 | .535 | 5-5 | W1 | 144 |
| 9/15/2021 | | | LAA | W | Abreu, J | 10 | 0 | 78 | 67 | .538 | 5-5 | W2 | 145 |
| 9/16/2021 | | | LAA | L | | 3 | 5 | 78 | 68 | .534 | 5-5 | L1 | 146 |
| 9/17/2021 | | @ | Tex | W | Anderson, T | 8 | 1 | 79 | 68 | .537 | 6-4 | W1 | 147 |
| 9/18/2021 | | @ | Tex | W | Goodwin, B | 3 | 2 | 80 | 68 | .541 | 6-4 | W2 | 148 |
| 9/19/2021 | | @ | Tex | L | | 7 | 8 | 80 | 69 | .537 | 6-4 | L1 | 149 |
| 9/20/2021 | | @ | Det | L | | 5 | 13 | 80 | 70 | .533 | 5-5 | L2 | 150 |
| 9/21/2021 | | @ | Det | W | Anderson, T | 4 | 0 | 81 | 70 | .536 | 5-5 | W1 | 151 |
| 9/23/2021 | 1 | @ | Cle | W | Grandal, Y | 3 | 2 | 82 | 70 | .539 | 6-4 | W2 | 152 |
| 9/23/2021 | 2 | @ | Cle | L | | 0 | 2 | 82 | 71 | .536 | 6-4 | L1 | 153 |
| 9/24/2021 | | @ | Cle | W | Jimenez, E | 4 | 2 | 83 | 71 | .539 | 6-4 | W1 | 154 |
| 9/25/2021 | | @ | Cle | W | Grandal, Y | 5 | 1 | 84 | 71 | .542 | 6-4 | W2 | 155 |
| 9/26/2021 | | @ | Cle | L | | 2 | 3 | 84 | 72 | .538 | 6-4 | L1 | 156 |
| 9/27/2021 | | @ | Det | L | | 0 | 10 | 84 | 73 | .535 | 5-5 | L2 | 157 |
| 9/28/2021 | | | Cin | W | Garcia, L | 6 | 2 | 85 | 73 | .538 | 5-5 | W1 | 158 |
| 9/29/2021 | | | Cin | W | Engel, A | 8 | 0 | 86 | 73 | .541 | 6-4 | W2 | 159 |
| 10/1/2021 | | | Det | W | Robert, L | 9 | 2 | 87 | 73 | .544 | 7-3 | W3 | 160 |
| 10/2/2021 | | | Det | W | Jimenez, E | 4 | 3 | 88 | 73 | .547 | 7-3 | W4 | 161 |
| 10/3/2021 | | | Det | W | Robert, L | 7 | 2 | 89 | 73 | .549 | 7-3 | W5 | 162 |