Team game results - 2021 Boston
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 10/4/2005 | 1 | | ChA | L | 2-6 | | | R | | | | R |
| 4/2/2021 | | | Bal | W | 5-0 | | Eovaldi, N | R | Eovaldi, N | | Means, J | L |
| 4/3/2021 | | | Bal | L | 1-3 | | Houck, T | R | Ottavino, A | | Harvey, M | R |
| 4/4/2021 | | | Bal | W | 4-1 | | Richards, G | R | Richards, G | Barnes, M | Zimmermann, B | L |
| 4/5/2021 | | | Tam | W | 3-2 | | Pivetta, N | R | Barnes, M | | Wacha, M | R |
| 4/6/2021 | | | Tam | L | 1-2 | | Perez, M | L | Perez, M | | Glasnow, T | R |
| 4/7/2021 | | | Tam | W | 7-4 | | Eovaldi, N | R | Eovaldi, N | Whitlock, G | Yarbrough, R | L |
| 4/8/2021 | | @ | Bal | W | 12-4 | | Rodriguez, E | L | Rodriguez, E | | Harvey, M | R |
| 4/10/2021 | | @ | Bal | W | 13-3 | | Richards, G | R | Richards, G | | Zimmermann, B | L |
| 4/11/2021 | | @ | Bal | W | 4-0 | | Pivetta, N | R | Pivetta, N | | Lopez, J | R |
| 4/13/2021 | | @ | Min | W | 9-8 | | Perez, M | L | Hernandez, D | Barnes, M | Happ, J | L |
| 4/14/2021 | 1 | @ | Min | W | 2-1 | 7 | Eovaldi, N | R | Eovaldi, N | | Maeda, K | R |
| 4/14/2021 | 2 | @ | Min | L | 1-2 | 7 | Rodriguez, E | L | Rodriguez, E | | Berrios, J | R |
| 4/15/2021 | | @ | Min | W | 9-5 | | Richards, G | R | Richards, G | | Pineda, M | R |
| 4/17/2021 | | | ChA | L | 1-3 | | Pivetta, N | R | Pivetta, N | | Cease, D | R |
| 4/18/2021 | 1 | | ChA | W | 4-3 | 7 | Houck, T | R | Whitlock, G | Barnes, M | Keuchel, D | L |
| 4/18/2021 | 2 | | ChA | L | 2-3 | 7 | Perez, M | L | Perez, M | | Kopech, M | R |
| 4/19/2021 | | | ChA | L | 2-3 | | Eovaldi, N | R | Sawamura, H | | Giolito, L | R |
| 4/20/2021 | | | Tor | W | 3-2 | | Rodriguez, E | L | Barnes, M | | Ryu, H | L |
| 4/21/2021 | | | Tor | L | 3-5 | | Richards, G | R | Richards, G | | Thornton, T | R |
| 4/22/2021 | | | Sea | W | 5-4 | 10 | Pivetta, N | R | Hernandez, D | | Dunn, J | R |
| 4/23/2021 | | | Sea | W | 9-8 | | Perez, M | L | Whitlock, G | | Kikuchi, Y | L |
| 4/24/2021 | | | Sea | W | 13-0 | | Eovaldi, N | R | Eovaldi, N | | Flexen, C | R |
| 4/25/2021 | | | Sea | W | 14-0 | | Rodriguez, E | L | Rodriguez, E | | Margevicius, N | L |
| 4/27/2021 | | @ | NYN | L | 1-6 | | Richards, G | R | Richards, G | | Peterson, D | L |
| 4/28/2021 | | @ | NYN | L | 0-6 | | Pivetta, N | R | Pivetta, N | | deGrom, J | R |
| 4/29/2021 | | @ | Tex | L | 1-2 | 11 | Perez, M | L | Whitlock, G | | Gibson, K | R |
| 4/30/2021 | | @ | Tex | W | 10-5 | | Eovaldi, N | R | Eovaldi, N | | Arihara, K | R |
| 5/1/2021 | | @ | Tex | L | 5-8 | | Rodriguez, E | L | Rodriguez, E | | Lyles, J | R |
| 5/2/2021 | | @ | Tex | W | 4-2 | | Richards, G | R | Richards, G | Barnes, M | Foltynewicz, M | R |
| 5/4/2021 | | | Det | W | 4-2 | | Pivetta, N | R | Andriese, M | Ottavino, A | Fulmer, M | R |
| 5/5/2021 | | | Det | W | 7-4 | | Perez, M | L | Perez, M | Barnes, M | Mize, C | R |
| 5/6/2021 | | | Det | W | 3-0 | | Eovaldi, N | R | Valdez, P | Ottavino, A | Turnbull, S | R |
| 5/7/2021 | | @ | Bal | L | 3-6 | | Rodriguez, E | L | Rodriguez, E | | Harvey, M | R |
| 5/8/2021 | | @ | Bal | W | 6-1 | | Richards, G | R | Richards, G | | Lowther, Z | L |
| 5/9/2021 | | @ | Bal | L | 5-8 | | Pivetta, N | R | Taylor, J | | Kremer, D | R |
| 5/10/2021 | | @ | Bal | L | 5-7 | | Perez, M | L | Sawamura, H | | Lopez, J | R |
| 5/11/2021 | | | Oak | L | 3-9 | | Eovaldi, N | R | Eovaldi, N | | Bassitt, C | R |
| 5/12/2021 | | | Oak | L | 3-11 | | Rodriguez, E | L | Rodriguez, E | | Kaprielian, J | R |
| 5/13/2021 | | | Oak | L | 2-3 | | Richards, G | R | Taylor, J | | Manaea, S | L |
| 5/14/2021 | | | LAA | W | 4-3 | | Pivetta, N | R | Barnes, M | | Canning, G | R |
| 5/15/2021 | | | LAA | L | 6-10 | | Perez, M | L | Andriese, M | | Bundy, D | R |
| 5/16/2021 | | | LAA | W | 6-2 | | Eovaldi, N | R | Eovaldi, N | | Quintana, J | L |
| 5/18/2021 | | @ | Tor | L | 2-4 | | Rodriguez, E | L | Rodriguez, E | | Ryu, H | L |
| 5/19/2021 | | @ | Tor | L | 2-9 | | Richards, G | R | Richards, G | | Stripling, R | R |
| 5/20/2021 | | @ | Tor | W | 8-5 | | Pivetta, N | R | Barnes, M | | Matz, S | L |
| 5/21/2021 | | @ | Phi | L | 0-4 | | Perez, M | L | Perez, M | | Nola, A | R |
| 5/22/2021 | | @ | Phi | L | 1-5 | | Eovaldi, N | R | Eovaldi, N | | Howard, S | R |
| 5/23/2021 | | @ | Phi | L | 3-6 | | Rodriguez, E | L | Rodriguez, E | | Wheeler, Z | R |
| 5/25/2021 | | | Atl | L | 5-9 | | Richards, G | R | Richards, G | | Morton, C | R |
| 5/26/2021 | | | Atl | W | 9-3 | | Pivetta, N | R | Pivetta, N | | Smyly, D | L |
| 5/28/2021 | | | Mia | W | 2-1 | | Perez, M | L | Perez, M | Barnes, M | Poteet, C | R |
| 5/29/2021 | | | Mia | L | 1-8 | | Eovaldi, N | R | Eovaldi, N | | Rogers, T | L |
| 5/31/2021 | | @ | Hou | W | 9-2 | | Rodriguez, E | L | Rodriguez, E | | Urquidy, J | R |
| 6/1/2021 | | @ | Hou | L | 1-6 | | Richards, G | R | Richards, G | | Garcia, L | R |
| 6/2/2021 | | @ | Hou | L | 1-4 | | Pivetta, N | R | Pivetta, N | | Valdez, F | L |
| 6/3/2021 | | @ | Hou | W | 4-0 | | Perez, M | L | Perez, M | | Odorizzi, J | R |
| 6/4/2021 | | @ | NYA | L | 0-1 | | Eovaldi, N | R | Whitlock, G | | King, M | R |
| 6/5/2021 | | @ | NYA | L | 4-6 | | Rodriguez, E | L | Workman, B | | Taillon, J | R |
| 6/6/2021 | | @ | NYA | W | 5-4 | | Richards, G | R | Richards, G | Barnes, M | German, D | R |
| 6/7/2021 | | | Mia | W | 4-0 | | Pivetta, N | R | Pivetta, N | | Thompson, Z | R |
| 6/8/2021 | | | Hou | L | 3-8 | | Perez, M | L | Perez, M | | Valdez, F | L |
| 6/9/2021 | | | Hou | W | 7-5 | | Eovaldi, N | R | Eovaldi, N | Barnes, M | Odorizzi, J | R |
| 6/10/2021 | | | Hou | L | 2-4 | | Rodriguez, E | L | Rodriguez, E | | Greinke, Z | R |
| 6/11/2021 | | | Tor | L | 4-7 | | Richards, G | R | Richards, G | | Stripling, R | R |
| 6/12/2021 | | | Tor | L | 8-14 | | Pivetta, N | R | Pivetta, N | | Matz, S | L |
| 6/13/2021 | | | Tor | W | 6-4 | | Perez, M | L | Whitlock, G | Barnes, M | Ray, R | L |
| 6/14/2021 | | | Tor | L | 3-7 | | Eovaldi, N | R | Hernandez, D | | Manoah, A | R |
| 6/15/2021 | | @ | Atl | W | 4-0 | | Rodriguez, E | L | Rodriguez, E | | Davidson, T | L |
| 6/16/2021 | | @ | Atl | W | 5-3 | | Richards, G | R | Richards, G | Barnes, M | Anderson, I | R |
| 6/18/2021 | | @ | KC | W | 9-6 | | Pivetta, N | R | Pivetta, N | Barnes, M | Zimmer, K | R |
| 6/19/2021 | | @ | KC | L | 0-5 | | Perez, M | L | Perez, M | | Keller, B | R |
| 6/20/2021 | | @ | KC | L | 2-4 | | Eovaldi, N | R | Eovaldi, N | | Minor, M | L |
| 6/22/2021 | | @ | Tam | L | 1-2 | | Rodriguez, E | L | Whitlock, G | | Kittredge, A | R |
| 6/23/2021 | | @ | Tam | L | 2-10 | | Richards, G | R | Richards, G | | Hill, R | L |
| 6/24/2021 | | @ | Tam | W | 3-1 | | Pivetta, N | R | Ottavino, A | Barnes, M | Wacha, M | R |
| 6/25/2021 | | | NYA | W | 8-7 | | Perez, M | L | Barnes, M | | German, D | R |
| 6/26/2021 | | | NYA | L | 2-11 | | Eovaldi, N | R | Eovaldi, N | | Montgomery, J | L |
| 6/27/2021 | | | NYA | W | 1-0 | | Rodriguez, E | L | Rodriguez, E | Ottavino, A | Cole, G | R |
| 6/28/2021 | | | KC | L | 6-12 | | Richards, G | R | Richards, G | | Duffy, D | L |
| 6/29/2021 | | | KC | L | 2-4 | | Pivetta, N | R | Pivetta, N | | Keller, B | R |
| 6/30/2021 | | | KC | L | 4-6 | | Perez, M | L | Whitlock, G | | Minor, M | L |
| 7/1/2021 | | | KC | W | 4-3 | | Eovaldi, N | R | Workman, B | | Bubic, K | L |
| 7/2/2021 | | @ | Oak | L | 2-4 | | Rodriguez, E | L | Rodriguez, E | | Montas, F | R |
| 7/3/2021 | | @ | Oak | L | 3-4 | | Richards, G | R | Richards, G | | Irvin, C | L |
| 7/4/2021 | | @ | Oak | L | 3-7 | | Pivetta, N | R | Pivetta, N | | Kaprielian, J | R |
| 7/5/2021 | | @ | LAA | W | 3-1 | | Perez, M | L | Perez, M | Barnes, M | Suarez, J | L |
| 7/6/2021 | | @ | LAA | W | 5-0 | | Eovaldi, N | R | Eovaldi, N | | Ohtani, S | R |
| 7/7/2021 | | @ | LAA | L | 0-2 | | Rodriguez, E | L | Rodriguez, E | | Heaney, A | L |
| 7/9/2021 | | | Phi | W | 8-1 | | Richards, G | R | Richards, G | | Velasquez, V | R |
| 7/10/2021 | | | Phi | W | 12-0 | | Perez, M | L | Perez, M | | Moore, M | L |
| 7/11/2021 | | | Phi | W | 12-6 | | Pivetta, N | R | Pivetta, N | | Kintzler, B | R |
| 7/16/2021 | | @ | NYA | W | 9-8 | | Rodriguez, E | L | Ottavino, A | Barnes, M | Montgomery, J | L |
| 7/17/2021 | | @ | NYA | W | 7-2 | | Eovaldi, N | R | Eovaldi, N | | Cole, G | R |
| 7/18/2021 | | @ | NYA | W | 7-4 | | Perez, M | L | Perez, M | Barnes, M | Taillon, J | R |
| 7/19/2021 | | @ | Tor | L | 10-11 | | Pivetta, N | R | Taylor, J | | Stripling, R | R |
| 7/21/2021 | | @ | Tor | W | 7-6 | | Richards, G | R | Richards, G | Barnes, M | Ray, R | L |
| 7/22/2021 | | | NYA | W | 3-1 | | Houck, T | R | Houck, T | Barnes, M | Montgomery, J | L |
| 7/23/2021 | | | NYA | W | 9-6 | | Rodriguez, E | L | Rios, Y | Ottavino, A | Cole, G | R |
| 7/24/2021 | | | NYA | W | 6-5 | 10 | Eovaldi, N | R | Hernandez, D | | Taillon, J | R |
| 7/25/2021 | | | NYA | W | 11-7 | | Perez, M | L | Perez, M | Whitlock, G | German, D | R |
| 7/26/2021 | | | Tor | W | 8-7 | | Pivetta, N | R | Valdez, P | Whitlock, G | Hatch, T | R |
| 7/28/2021 | 1 | | Tor | L | 0-8 | 7 | Richards, G | R | Richards, G | | Ray, R | L |
| 7/28/2021 | 2 | | Tor | L | 1-8 | 7 | Houck, T | R | Houck, T | | Matz, S | L |
| 7/29/2021 | | | Tor | L | 3-6 | | Rodriguez, E | L | Rodriguez, E | | Ryu, H | L |
| 7/30/2021 | | @ | Tam | L | 5-6 | | Perez, M | L | Rios, Y | | Fleming, J | L |
| 7/31/2021 | | @ | Tam | L | 1-2 | | Eovaldi, N | R | Eovaldi, N | | Yarbrough, R | L |
| 8/1/2021 | | @ | Tam | L | 0-9 | | Pivetta, N | R | Pivetta, N | | McClanahan, S | L |
| 8/3/2021 | | @ | Det | L | 3-7 | | Richards, G | R | Richards, G | | Peralta, W | R |
| 8/4/2021 | | @ | Det | L | 0-6 | | Rodriguez, E | L | Rodriguez, E | | Mize, C | R |
| 8/5/2021 | | @ | Det | L | 1-12 | | Perez, M | L | Perez, M | | Skubal, T | L |
| 8/6/2021 | | @ | Tor | W | 9-4 | | Eovaldi, N | R | Eovaldi, N | | Manoah, A | R |
| 8/7/2021 | 1 | @ | Tor | W | 5-1 | 7 | Pivetta, N | R | Pivetta, N | | Ray, R | L |
| 8/7/2021 | 2 | @ | Tor | L | 0-5 | 7 | Houck, T | R | Houck, T | | Berrios, J | R |
| 8/8/2021 | | @ | Tor | L | 5-13 | | Richards, G | R | Richards, G | | Ryu, H | L |
| 8/10/2021 | | | Tam | W | 3-2 | | Rodriguez, E | L | Robles, H | Barnes, M | Patino, L | R |
| 8/11/2021 | | | Tam | W | 5-4 | | Eovaldi, N | R | Eovaldi, N | Barnes, M | Fleming, J | L |
| 8/12/2021 | | | Tam | W | 8-5 | | Houck, T | R | Houck, T | Robles, H | Rasmussen, D | R |
| 8/13/2021 | | | Bal | W | 5-4 | | Pivetta, N | R | Pivetta, N | Robles, H | Watkins, S | R |
| 8/14/2021 | | | Bal | W | 5-3 | | Sale, C | L | Richards, G | | Lopez, J | R |
| 8/15/2021 | | | Bal | L | 1-3 | | Rodriguez, E | L | Rodriguez, E | | Akin, K | L |
| 8/17/2021 | 1 | @ | NYA | L | 2-3 | 7 | Houck, T | R | Robles, H | | Montgomery, J | L |
| 8/17/2021 | 2 | @ | NYA | W | 8-3 | 7 | Eovaldi, N | R | Eovaldi, N | | Gil, L | R |
| 8/18/2021 | | @ | NYA | W | 4-2 | | Pivetta, N | R | Pivetta, N | Barnes, M | Heaney, A | L |
| 8/20/2021 | | | Tex | W | 3-1 | | Sale, C | L | Sale, C | Barnes, M | Dunning, D | R |
| 8/21/2021 | | | Tex | W | 13-4 | | Rodriguez, E | L | Rodriguez, E | | Lyles, J | R |
| 8/23/2021 | | | Tex | W | 7-6 | 10 | Eovaldi, N | R | Barnes, M | | Allard, K | L |
| 8/24/2021 | | | Min | W | 13-1 | | Houck, T | R | Houck, T | | Jax, G | R |
| 8/25/2021 | | | Min | L | 2-6 | | Pivetta, N | R | Pivetta, N | | Ober, B | R |
| 8/26/2021 | | | Min | W | 10-3 | | Sale, C | L | Sale, C | | Gant, J | R |
| 8/27/2021 | | @ | Cle | W | 4-1 | | Rodriguez, E | L | Richards, G | Robles, H | Allen, L | L |
| 8/28/2021 | | @ | Cle | L | 2-3 | 10 | Eovaldi, N | R | Ottavino, A | | Quantrill, C | R |
| 8/29/2021 | | @ | Cle | W | 10-3 | | Houck, T | R | Houck, T | | Morgan, E | R |
| 8/30/2021 | | @ | Tam | W | 5-3 | | Pivetta, N | R | Pivetta, N | Richards, G | Patino, L | R |
| 8/31/2021 | | @ | Tam | L | 4-7 | | Peacock, B | R | Richards, G | | Yarbrough, R | L |
| 9/1/2021 | | @ | Tam | L | 8-9 | | Sale, C | L | Whitlock, G | | Rasmussen, D | R |
| 9/2/2021 | | @ | Tam | L | 8-9 | 10 | Rodriguez, E | L | Ottavino, A | | McClanahan, S | L |
| 9/3/2021 | | | Cle | L | 0-11 | | Eovaldi, N | R | Eovaldi, N | | Quantrill, C | R |
| 9/4/2021 | | | Cle | W | 3-1 | | Houck, T | R | Whitlock, G | Ottavino, A | Morgan, E | R |
| 9/5/2021 | | | Cle | W | 7-4 | | Crawford, K | R | Gonsalves, S | Ottavino, A | Plesac, Z | R |
| 9/6/2021 | | | Tam | L | 4-5 | | Sale, C | L | Whitlock, G | | Yarbrough, R | L |
| 9/7/2021 | | | Tam | L | 2-9 | | Rodriguez, E | L | Rodriguez, E | | Rasmussen, D | R |
| 9/8/2021 | | | Tam | W | 9-8 | 10 | Eovaldi, N | R | Robles, H | | McClanahan, S | L |
| 9/10/2021 | | @ | ChA | L | 0-7 | | Houck, T | R | Houck, T | | Rodon, C | L |
| 9/11/2021 | | @ | ChA | W | 5-4 | | Seabold, C | R | Hernandez, D | Ottavino, A | Cease, D | R |
| 9/12/2021 | | @ | ChA | W | 13-0 | | Pivetta, N | R | Pivetta, N | | Lynn, L | R |
| 9/13/2021 | | @ | Sea | L | 1-4 | | Rodriguez, E | L | Hernandez, D | | Gilbert, L | R |
| 9/14/2021 | | @ | Sea | W | 3-1 | | Eovaldi, N | R | Eovaldi, N | Robles, H | Anderson, T | L |
| 9/15/2021 | | @ | Sea | W | 7-1 | | Houck, T | R | Houck, T | | Gonzales, M | L |
| 9/17/2021 | | | Bal | W | 6-5 | | Sale, C | L | Barnes, M | | Akin, K | L |
| 9/18/2021 | | | Bal | W | 11-5 | | Pivetta, N | R | Pivetta, N | | Lowther, Z | L |
| 9/19/2021 | | | Bal | L | 8-11 | | Eovaldi, N | R | Sawamura, H | | Wells, A | L |
| 9/21/2021 | | | NYN | L | 7-8 | | Rodriguez, E | L | Barnes, M | | Stroman, M | R |
| 9/22/2021 | | | NYN | W | 4-2 | | Sale, C | L | Sale, C | Ottavino, A | Walker, T | R |
| 9/24/2021 | | | NYA | W | 6-0 | | Eovaldi, N | R | Eovaldi, N | | Cole, G | R |
| 9/25/2021 | | | NYA | W | 9-4 | | Pivetta, N | R | Pivetta, N | | Cortes, N | L |
| 9/26/2021 | | | NYA | L | 3-6 | | Rodriguez, E | L | Ottavino, A | | Montgomery, J | L |
| 9/28/2021 | | @ | Bal | L | 7-8 | | Sale, C | L | Robles, H | | Zimmermann, B | L |
| 9/29/2021 | | @ | Bal | W | 10-6 | | Eovaldi, N | R | Eovaldi, N | | Lowther, Z | L |
| 9/30/2021 | | @ | Bal | W | 8-4 | | Pivetta, N | R | Richards, G | | Wells, A | L |
| 10/1/2021 | | @ | Was | W | 7-5 | | Rodriguez, E | L | Robles, H | Barnes, M | Rogers, J | L |
| 10/2/2021 | | @ | Was | W | 8-6 | | Houck, T | R | Perez, M | | Gray, J | R |
| 10/3/2021 | | @ | Was | W | 7-3 | | Sale, C | L | Whitlock, G | | Adon, J | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 10/4/2005 | 1 | | ChA | L | | 2 | 6 | 88 | 75 | .540 | 7-3 | L1 | 163 |
| 4/2/2021 | | | Bal | W | Hernandez, E | 5 | 0 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/3/2021 | | | Bal | L | | 1 | 3 | 1 | 1 | .500 | 1-1 | L1 | 2 |
| 4/4/2021 | | | Bal | W | | 4 | 1 | 2 | 1 | .667 | 2-1 | W1 | 3 |
| 4/5/2021 | | | Tam | W | Cordero, F | 3 | 2 | 3 | 1 | .750 | 3-1 | W2 | 4 |
| 4/6/2021 | | | Tam | L | | 1 | 2 | 3 | 2 | .600 | 3-2 | L1 | 5 |
| 4/7/2021 | | | Tam | W | Arroyo, C | 7 | 4 | 4 | 2 | .667 | 4-2 | W1 | 6 |
| 4/8/2021 | | @ | Bal | W | Devers, R | 12 | 4 | 5 | 2 | .714 | 5-2 | W2 | 7 |
| 4/10/2021 | | @ | Bal | W | Bogaerts, X | 13 | 3 | 6 | 2 | .750 | 6-2 | W3 | 8 |
| 4/11/2021 | | @ | Bal | W | Devers, R | 4 | 0 | 7 | 2 | .778 | 7-2 | W4 | 9 |
| 4/13/2021 | | @ | Min | W | Bogaerts, X | 9 | 8 | 8 | 2 | .800 | 8-2 | W5 | 10 |
| 4/14/2021 | 1 | @ | Min | W | Verdugo, A | 2 | 1 | 9 | 2 | .818 | 8-2 | W6 | 11 |
| 4/14/2021 | 2 | @ | Min | L | | 1 | 2 | 9 | 3 | .750 | 8-2 | L1 | 12 |
| 4/15/2021 | | @ | Min | W | Devers, R | 9 | 5 | 10 | 3 | .769 | 8-2 | W1 | 13 |
| 4/17/2021 | | | ChA | L | | 1 | 3 | 10 | 4 | .714 | 7-3 | L1 | 14 |
| 4/18/2021 | 1 | | ChA | W | Bogaerts, X | 4 | 3 | 11 | 4 | .733 | 8-2 | W1 | 15 |
| 4/18/2021 | 2 | | ChA | L | | 2 | 3 | 11 | 5 | .688 | 7-3 | L1 | 16 |
| 4/19/2021 | | | ChA | L | | 2 | 3 | 11 | 6 | .647 | 6-4 | L2 | 17 |
| 4/20/2021 | | | Tor | W | | 3 | 2 | 12 | 6 | .667 | 6-4 | W1 | 18 |
| 4/21/2021 | | | Tor | L | | 3 | 5 | 12 | 7 | .632 | 5-5 | L1 | 19 |
| 4/22/2021 | | | Sea | W | Devers, R | 5 | 4 | 13 | 7 | .650 | 5-5 | W1 | 20 |
| 4/23/2021 | | | Sea | W | Vazquez, C | 9 | 8 | 14 | 7 | .667 | 5-5 | W2 | 21 |
| 4/24/2021 | | | Sea | W | Gonzalez, M | 13 | 0 | 15 | 7 | .682 | 6-4 | W3 | 22 |
| 4/25/2021 | | | Sea | W | Hernandez, E | 14 | 0 | 16 | 7 | .696 | 6-4 | W4 | 23 |
| 4/27/2021 | | @ | NYN | L | | 1 | 6 | 16 | 8 | .667 | 6-4 | L1 | 24 |
| 4/28/2021 | | @ | NYN | L | | 0 | 6 | 16 | 9 | .640 | 5-5 | L2 | 25 |
| 4/29/2021 | | @ | Tex | L | | 1 | 2 | 16 | 10 | .615 | 5-5 | L3 | 26 |
| 4/30/2021 | | @ | Tex | W | Renfroe, H | 10 | 5 | 17 | 10 | .630 | 6-4 | W1 | 27 |
| 5/1/2021 | | @ | Tex | L | | 5 | 8 | 17 | 11 | .607 | 5-5 | L1 | 28 |
| 5/2/2021 | | @ | Tex | W | Renfroe, H | 4 | 2 | 18 | 11 | .621 | 6-4 | W1 | 29 |
| 5/4/2021 | | | Det | W | Hernandez, E | 4 | 2 | 19 | 11 | .633 | 6-4 | W2 | 30 |
| 5/5/2021 | | | Det | W | Martinez, J | 7 | 4 | 20 | 11 | .645 | 6-4 | W3 | 31 |
| 5/6/2021 | | | Det | W | Devers, R | 3 | 0 | 21 | 11 | .656 | 6-4 | W4 | 32 |
| 5/7/2021 | | @ | Bal | L | | 3 | 6 | 21 | 12 | .636 | 5-5 | L1 | 33 |
| 5/8/2021 | | @ | Bal | W | | 6 | 1 | 22 | 12 | .647 | 6-4 | W1 | 34 |
| 5/9/2021 | | @ | Bal | L | | 5 | 8 | 22 | 13 | .629 | 6-4 | L1 | 35 |
| 5/10/2021 | | @ | Bal | L | | 5 | 7 | 22 | 14 | .611 | 6-4 | L2 | 36 |
| 5/11/2021 | | | Oak | L | | 3 | 9 | 22 | 15 | .595 | 5-5 | L3 | 37 |
| 5/12/2021 | | | Oak | L | | 3 | 11 | 22 | 16 | .579 | 5-5 | L4 | 38 |
| 5/13/2021 | | | Oak | L | | 2 | 3 | 22 | 17 | .564 | 4-6 | L5 | 39 |
| 5/14/2021 | | | LAA | W | Renfroe, H | 4 | 3 | 23 | 17 | .575 | 4-6 | W1 | 40 |
| 5/15/2021 | | | LAA | L | | 6 | 10 | 23 | 18 | .561 | 3-7 | L1 | 41 |
| 5/16/2021 | | | LAA | W | Dalbec, B | 6 | 2 | 24 | 18 | .571 | 3-7 | W1 | 42 |
| 5/18/2021 | | @ | Tor | L | | 2 | 4 | 24 | 19 | .558 | 3-7 | L1 | 43 |
| 5/19/2021 | | @ | Tor | L | | 2 | 9 | 24 | 20 | .545 | 2-8 | L2 | 44 |
| 5/20/2021 | | @ | Tor | W | Chavis, M | 8 | 5 | 25 | 20 | .556 | 3-7 | W1 | 45 |
| 5/21/2021 | | @ | Phi | L | | 0 | 4 | 25 | 21 | .543 | 3-7 | L1 | 46 |
| 5/22/2021 | | @ | Phi | L | | 1 | 5 | 25 | 22 | .532 | 3-7 | L2 | 47 |
| 5/23/2021 | | @ | Phi | L | | 3 | 6 | 25 | 23 | .521 | 3-7 | L3 | 48 |
| 5/25/2021 | | | Atl | L | | 5 | 9 | 25 | 24 | .510 | 3-7 | L4 | 49 |
| 5/26/2021 | | | Atl | W | Renfroe, H | 9 | 3 | 26 | 24 | .520 | 3-7 | W1 | 50 |
| 5/28/2021 | | | Mia | W | Martinez, J | 2 | 1 | 27 | 24 | .529 | 4-6 | W2 | 51 |
| 5/29/2021 | | | Mia | L | | 1 | 8 | 27 | 25 | .519 | 3-7 | L1 | 52 |
| 5/31/2021 | | @ | Hou | W | Hernandez, E | 9 | 2 | 28 | 25 | .528 | 4-6 | W1 | 53 |
| 6/1/2021 | | @ | Hou | L | | 1 | 6 | 28 | 26 | .519 | 4-6 | L1 | 54 |
| 6/2/2021 | | @ | Hou | L | | 1 | 4 | 28 | 27 | .509 | 3-7 | L2 | 55 |
| 6/3/2021 | | @ | Hou | W | Santana, D | 4 | 0 | 29 | 27 | .518 | 4-6 | W1 | 56 |
| 6/4/2021 | | @ | NYA | L | | 0 | 1 | 29 | 28 | .509 | 4-6 | L1 | 57 |
| 6/5/2021 | | @ | NYA | L | | 4 | 6 | 29 | 29 | .500 | 4-6 | L2 | 58 |
| 6/6/2021 | | @ | NYA | W | Bogaerts, X | 5 | 4 | 30 | 29 | .508 | 5-5 | W1 | 59 |
| 6/7/2021 | | | Mia | W | Devers, R | 4 | 0 | 31 | 29 | .517 | 5-5 | W2 | 60 |
| 6/8/2021 | | | Hou | L | | 3 | 8 | 31 | 30 | .508 | 4-6 | L1 | 61 |
| 6/9/2021 | | | Hou | W | Martinez, J | 7 | 5 | 32 | 30 | .516 | 5-5 | W1 | 62 |
| 6/10/2021 | | | Hou | L | | 2 | 4 | 32 | 31 | .508 | 4-6 | L1 | 63 |
| 6/11/2021 | | | Tor | L | | 4 | 7 | 32 | 32 | .500 | 4-6 | L2 | 64 |
| 6/12/2021 | | | Tor | L | | 8 | 14 | 32 | 33 | .492 | 4-6 | L3 | 65 |
| 6/13/2021 | | | Tor | W | Renfroe, H | 6 | 4 | 33 | 33 | .500 | 4-6 | W1 | 66 |
| 6/14/2021 | | | Tor | L | | 3 | 7 | 33 | 34 | .493 | 4-6 | L1 | 67 |
| 6/15/2021 | | @ | Atl | W | Dalbec, B | 4 | 0 | 34 | 34 | .500 | 5-5 | W1 | 68 |
| 6/16/2021 | | @ | Atl | W | | 5 | 3 | 35 | 34 | .507 | 5-5 | W2 | 69 |
| 6/18/2021 | | @ | KC | W | Martinez, J | 9 | 6 | 36 | 34 | .514 | 5-5 | W3 | 70 |
| 6/19/2021 | | @ | KC | L | | 0 | 5 | 36 | 35 | .507 | 5-5 | L1 | 71 |
| 6/20/2021 | | @ | KC | L | | 2 | 4 | 36 | 36 | .500 | 4-6 | L2 | 72 |
| 6/22/2021 | | @ | Tam | L | | 1 | 2 | 36 | 37 | .493 | 4-6 | L3 | 73 |
| 6/23/2021 | | @ | Tam | L | | 2 | 10 | 36 | 38 | .486 | 4-6 | L4 | 74 |
| 6/24/2021 | | @ | Tam | W | Hernandez, E | 3 | 1 | 37 | 38 | .493 | 5-5 | W1 | 75 |
| 6/25/2021 | | | NYA | W | Gonzalez, M | 8 | 7 | 38 | 38 | .500 | 5-5 | W2 | 76 |
| 6/26/2021 | | | NYA | L | | 2 | 11 | 38 | 39 | .494 | 5-5 | L1 | 77 |
| 6/27/2021 | | | NYA | W | Verdugo, A | 1 | 0 | 39 | 39 | .500 | 5-5 | W1 | 78 |
| 6/28/2021 | | | KC | L | | 6 | 12 | 39 | 40 | .494 | 4-6 | L1 | 79 |
| 6/29/2021 | | | KC | L | | 2 | 4 | 39 | 41 | .488 | 3-7 | L2 | 80 |
| 6/30/2021 | | | KC | L | | 4 | 6 | 39 | 42 | .481 | 3-7 | L3 | 81 |
| 7/1/2021 | | | KC | W | Verdugo, A | 4 | 3 | 40 | 42 | .488 | 4-6 | W1 | 82 |
| 7/2/2021 | | @ | Oak | L | | 2 | 4 | 40 | 43 | .482 | 4-6 | L1 | 83 |
| 7/3/2021 | | @ | Oak | L | | 3 | 4 | 40 | 44 | .476 | 4-6 | L2 | 84 |
| 7/4/2021 | | @ | Oak | L | | 3 | 7 | 40 | 45 | .471 | 3-7 | L3 | 85 |
| 7/5/2021 | | @ | LAA | W | Martinez, J | 3 | 1 | 41 | 45 | .477 | 3-7 | W1 | 86 |
| 7/6/2021 | | @ | LAA | W | Martinez, J | 5 | 0 | 42 | 45 | .483 | 4-6 | W2 | 87 |
| 7/7/2021 | | @ | LAA | L | | 0 | 2 | 42 | 46 | .477 | 3-7 | L1 | 88 |
| 7/9/2021 | | | Phi | W | Martinez, J | 8 | 1 | 43 | 46 | .483 | 4-6 | W1 | 89 |
| 7/10/2021 | | | Phi | W | Bogaerts, X | 12 | 0 | 44 | 46 | .489 | 5-5 | W2 | 90 |
| 7/11/2021 | | | Phi | W | Martinez, J | 12 | 6 | 45 | 46 | .495 | 6-4 | W3 | 91 |
| 7/16/2021 | | @ | NYA | W | Vazquez, C | 9 | 8 | 46 | 46 | .500 | 6-4 | W4 | 92 |
| 7/17/2021 | | @ | NYA | W | Hernandez, E | 7 | 2 | 47 | 46 | .505 | 7-3 | W5 | 93 |
| 7/18/2021 | | @ | NYA | W | Verdugo, A | 7 | 4 | 48 | 46 | .511 | 8-2 | W6 | 94 |
| 7/19/2021 | | @ | Tor | L | | 10 | 11 | 48 | 47 | .505 | 8-2 | L1 | 95 |
| 7/21/2021 | | @ | Tor | W | Bogaerts, X | 7 | 6 | 49 | 47 | .510 | 8-2 | W1 | 96 |
| 7/22/2021 | | | NYA | W | Martinez, J | 3 | 1 | 50 | 47 | .515 | 8-2 | W2 | 97 |
| 7/23/2021 | | | NYA | W | Vazquez, C | 9 | 6 | 51 | 47 | .520 | 9-1 | W3 | 98 |
| 7/24/2021 | | | NYA | W | Bogaerts, X | 6 | 5 | 52 | 47 | .525 | 9-1 | W4 | 99 |
| 7/25/2021 | | | NYA | W | Renfroe, H | 11 | 7 | 53 | 47 | .530 | 9-1 | W5 | 100 |
| 7/26/2021 | | | Tor | W | Vazquez, C | 8 | 7 | 54 | 47 | .535 | 9-1 | W6 | 101 |
| 7/28/2021 | 1 | | Tor | L | | 0 | 8 | 54 | 48 | .529 | 8-2 | L1 | 102 |
| 7/28/2021 | 2 | | Tor | L | | 1 | 8 | 54 | 49 | .524 | 7-3 | L2 | 103 |
| 7/29/2021 | | | Tor | L | | 3 | 6 | 54 | 50 | .519 | 6-4 | L3 | 104 |
| 7/30/2021 | | @ | Tam | L | | 5 | 6 | 54 | 51 | .514 | 6-4 | L4 | 105 |
| 7/31/2021 | | @ | Tam | L | | 1 | 2 | 54 | 52 | .509 | 5-5 | L5 | 106 |
| 8/1/2021 | | @ | Tam | L | | 0 | 9 | 54 | 53 | .505 | 4-6 | L6 | 107 |
| 8/3/2021 | | @ | Det | L | | 3 | 7 | 54 | 54 | .500 | 3-7 | L7 | 108 |
| 8/4/2021 | | @ | Det | L | | 0 | 6 | 54 | 55 | .495 | 2-8 | L8 | 109 |
| 8/5/2021 | | @ | Det | L | | 1 | 12 | 54 | 56 | .491 | 1-9 | L9 | 110 |
| 8/6/2021 | | @ | Tor | W | Renfroe, H | 9 | 4 | 55 | 56 | .495 | 1-9 | W1 | 111 |
| 8/7/2021 | 1 | @ | Tor | W | Arauz, J | 5 | 1 | 56 | 56 | .500 | 2-8 | W2 | 112 |
| 8/7/2021 | 2 | @ | Tor | L | | 0 | 5 | 56 | 57 | .496 | 2-8 | L1 | 113 |
| 8/8/2021 | | @ | Tor | L | | 5 | 13 | 56 | 58 | .491 | 2-8 | L2 | 114 |
| 8/10/2021 | | | Tam | W | | 3 | 2 | 57 | 58 | .496 | 3-7 | W1 | 115 |
| 8/11/2021 | | | Tam | W | Hernandez, E | 5 | 4 | 58 | 58 | .500 | 4-6 | W2 | 116 |
| 8/12/2021 | | | Tam | W | Cordero, F | 8 | 5 | 59 | 58 | .504 | 5-5 | W3 | 117 |
| 8/13/2021 | | | Bal | W | Verdugo, A | 5 | 4 | 60 | 58 | .508 | 6-4 | W4 | 118 |
| 8/14/2021 | | | Bal | W | Hernandez, E | 5 | 3 | 61 | 58 | .513 | 7-3 | W5 | 119 |
| 8/15/2021 | | | Bal | L | | 1 | 3 | 61 | 59 | .508 | 7-3 | L1 | 120 |
| 8/17/2021 | 1 | @ | NYA | L | | 2 | 3 | 61 | 60 | .504 | 6-4 | L2 | 121 |
| 8/17/2021 | 2 | @ | NYA | W | Martinez, J | 8 | 3 | 62 | 60 | .508 | 6-4 | W1 | 122 |
| 8/18/2021 | | @ | NYA | W | Martinez, J | 4 | 2 | 63 | 60 | .512 | 7-3 | W2 | 123 |
| 8/20/2021 | | | Tex | W | Hernandez, E | 3 | 1 | 64 | 60 | .516 | 8-2 | W3 | 124 |
| 8/21/2021 | | | Tex | W | Martinez, J | 13 | 4 | 65 | 60 | .520 | 8-2 | W4 | 125 |
| 8/23/2021 | | | Tex | W | Hernandez, E | 7 | 6 | 66 | 60 | .524 | 8-2 | W5 | 126 |
| 8/24/2021 | | | Min | W | Devers, R | 13 | 1 | 67 | 60 | .528 | 8-2 | W6 | 127 |
| 8/25/2021 | | | Min | L | | 2 | 6 | 67 | 61 | .523 | 7-3 | L1 | 128 |
| 8/26/2021 | | | Min | W | Dalbec, B | 10 | 3 | 68 | 61 | .527 | 7-3 | W1 | 129 |
| 8/27/2021 | | @ | Cle | W | Dalbec, B | 4 | 1 | 69 | 61 | .531 | 8-2 | W2 | 130 |
| 8/28/2021 | | @ | Cle | L | | 2 | 3 | 69 | 62 | .527 | 8-2 | L1 | 131 |
| 8/29/2021 | | @ | Cle | W | | 10 | 3 | 70 | 62 | .530 | 8-2 | W1 | 132 |
| 8/30/2021 | | @ | Tam | W | Devers, R | 5 | 3 | 71 | 62 | .534 | 8-2 | W2 | 133 |
| 8/31/2021 | | @ | Tam | L | | 4 | 7 | 71 | 63 | .530 | 7-3 | L1 | 134 |
| 9/1/2021 | | @ | Tam | L | | 8 | 9 | 71 | 64 | .526 | 6-4 | L2 | 135 |
| 9/2/2021 | | @ | Tam | L | | 8 | 9 | 71 | 65 | .522 | 5-5 | L3 | 136 |
| 9/3/2021 | | | Cle | L | | 0 | 11 | 71 | 66 | .518 | 4-6 | L4 | 137 |
| 9/4/2021 | | | Cle | W | Verdugo, A | 3 | 1 | 72 | 66 | .522 | 5-5 | W1 | 138 |
| 9/5/2021 | | | Cle | W | Shaw, T | 7 | 4 | 73 | 66 | .525 | 5-5 | W2 | 139 |
| 9/6/2021 | | | Tam | L | | 4 | 5 | 73 | 67 | .521 | 4-6 | L1 | 140 |
| 9/7/2021 | | | Tam | L | | 2 | 9 | 73 | 68 | .518 | 4-6 | L2 | 141 |
| 9/8/2021 | | | Tam | W | Verdugo, A | 9 | 8 | 74 | 68 | .521 | 4-6 | W1 | 142 |
| 9/10/2021 | | @ | ChA | L | | 0 | 7 | 74 | 69 | .517 | 3-7 | L1 | 143 |
| 9/11/2021 | | @ | ChA | W | Vazquez, C | 5 | 4 | 75 | 69 | .521 | 4-6 | W1 | 144 |
| 9/12/2021 | | @ | ChA | W | Schwarber, K | 13 | 0 | 76 | 69 | .524 | 5-5 | W2 | 145 |
| 9/13/2021 | | @ | Sea | L | | 1 | 4 | 76 | 70 | .521 | 5-5 | L1 | 146 |
| 9/14/2021 | | @ | Sea | W | Devers, R | 3 | 1 | 77 | 70 | .524 | 6-4 | W1 | 147 |
| 9/15/2021 | | @ | Sea | W | Hernandez, E | 7 | 1 | 78 | 70 | .527 | 6-4 | W2 | 148 |
| 9/17/2021 | | | Bal | W | Bogaerts, X | 6 | 5 | 79 | 70 | .530 | 6-4 | W3 | 149 |
| 9/18/2021 | | | Bal | W | Renfroe, H | 11 | 5 | 80 | 70 | .533 | 7-3 | W4 | 150 |
| 9/19/2021 | | | Bal | L | | 8 | 11 | 80 | 71 | .530 | 7-3 | L1 | 151 |
| 9/21/2021 | | | NYN | L | | 7 | 8 | 80 | 72 | .526 | 6-4 | L2 | 152 |
| 9/22/2021 | | | NYN | W | Devers, R | 4 | 2 | 81 | 72 | .529 | 7-3 | W1 | 153 |
| 9/24/2021 | | | NYA | W | Martinez, J | 6 | 0 | 82 | 72 | .532 | 7-3 | W2 | 154 |
| 9/25/2021 | | | NYA | W | Hernandez, E | 9 | 4 | 83 | 72 | .535 | 7-3 | W3 | 155 |
| 9/26/2021 | | | NYA | L | | 3 | 6 | 83 | 73 | .532 | 7-3 | L1 | 156 |
| 9/28/2021 | | @ | Bal | L | | 7 | 8 | 83 | 74 | .529 | 6-4 | L2 | 157 |
| 9/29/2021 | | @ | Bal | W | | 10 | 6 | 84 | 74 | .532 | 6-4 | W1 | 158 |
| 9/30/2021 | | @ | Bal | W | Renfroe, H | 8 | 4 | 85 | 74 | .535 | 6-4 | W2 | 159 |
| 10/1/2021 | | @ | Was | W | Martinez, J | 7 | 5 | 86 | 74 | .538 | 6-4 | W3 | 160 |
| 10/2/2021 | | @ | Was | W | Martinez, J | 8 | 6 | 87 | 74 | .540 | 7-3 | W4 | 161 |
| 10/3/2021 | | @ | Was | W | Martinez, J | 7 | 3 | 88 | 74 | .543 | 8-2 | W5 | 162 |