Team game results - 2021 San Francisco
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/1/2021 | | @ | Sea | W | 5-3 | | Gausman, K | R | Gausman, K | McGee, J | Gonzales, M | L |
| 4/2/2021 | | @ | Sea | W | 6-5 | | Cueto, J | R | Cueto, J | McGee, J | Kikuchi, Y | L |
| 4/3/2021 | | @ | Sea | W | 6-1 | | Webb, L | R | Webb, L | | Flexen, C | R |
| 4/5/2021 | | @ | SD | W | 12-6 | | DeSclafani, A | R | DeSclafani, A | | Morejon, A | L |
| 4/6/2021 | | @ | SD | W | 3-2 | 10 | Sanchez, A | R | Baragar, C | McGee, J | Darvish, Y | R |
| 4/7/2021 | | @ | SD | W | 6-2 | | Gausman, K | R | Gausman, K | | Snell, B | L |
| 4/9/2021 | | | Col | L | 2-7 | | Cueto, J | R | Cueto, J | | Gomber, A | L |
| 4/10/2021 | | | Col | W | 3-2 | | Webb, L | R | Webb, L | McGee, J | Gonzalez, C | R |
| 4/11/2021 | | | Col | W | 7-0 | | DeSclafani, A | R | DeSclafani, A | | Marquez, G | R |
| 4/12/2021 | | | Cin | L | 0-1 | | Sanchez, A | R | Sanchez, A | | Miley, W | L |
| 4/13/2021 | | | Cin | W | 4-0 | | Gausman, K | R | Gausman, K | McGee, J | Castillo, L | R |
| 4/14/2021 | | | Cin | W | 14-2 | | Cueto, J | R | Cueto, J | | Mahle, T | R |
| 4/16/2021 | | @ | Mia | W | 9-5 | | DeSclafani, A | R | DeSclafani, A | | Castano, D | L |
| 4/17/2021 | | @ | Mia | L | 4-8 | | Sanchez, A | R | Baragar, C | | Alcantara, S | R |
| 4/18/2021 | | @ | Mia | W | 6-1 | | Wood, A | L | Wood, A | | Lopez, P | R |
| 4/19/2021 | | @ | Phi | W | 8-6 | | Gausman, K | R | Alvarez, J | Rogers, T | Anderson, C | R |
| 4/20/2021 | | @ | Phi | W | 7-3 | 10 | Webb, L | R | McGee, J | | Wheeler, Z | R |
| 4/21/2021 | | @ | Phi | L | 3-4 | | DeSclafani, A | R | DeSclafani, A | | Eflin, Z | R |
| 4/22/2021 | | | Mia | L | 0-1 | | Sanchez, A | R | Sanchez, A | | Castano, D | L |
| 4/23/2021 | | | Mia | W | 7-1 | | Wood, A | L | Wood, A | | Alcantara, S | R |
| 4/24/2021 | | | Mia | W | 6-5 | 10 | Gausman, K | R | Alvarez, J | | Lopez, P | R |
| 4/25/2021 | | | Mia | L | 5-8 | | Webb, L | R | Doval, C | | Detwiler, R | L |
| 4/26/2021 | | | Col | W | 5-4 | 10 | DeSclafani, A | R | Baragar, C | | Gomber, A | L |
| 4/27/2021 | | | Col | L | 3-9 | | Sanchez, A | R | Sanchez, A | | Gonzalez, C | R |
| 4/28/2021 | | | Col | W | 2-1 | | Wood, A | L | Rogers, T | | Marquez, G | R |
| 4/30/2021 | | @ | SD | W | 3-1 | | Webb, L | R | Webb, L | McGee, J | Darvish, Y | R |
| 5/1/2021 | | @ | SD | W | 12-6 | | DeSclafani, A | R | Doval, C | | Snell, B | L |
| 5/2/2021 | | @ | SD | W | 3-1 | | Gausman, K | R | Gausman, K | McGee, J | Musgrove, J | R |
| 5/4/2021 | 1 | @ | Col | L | 4-6 | 7 | Sanchez, A | R | Sanchez, A | | Marquez, G | R |
| 5/4/2021 | 2 | @ | Col | W | 1-0 | 7 | Wood, A | L | Wood, A | McGee, J | Castellani, R | R |
| 5/5/2021 | | @ | Col | L | 1-2 | | Webb, L | R | Webb, L | | Gray, J | R |
| 5/7/2021 | | | SD | W | 5-3 | | DeSclafani, A | R | DeSclafani, A | McGee, J | Snell, B | L |
| 5/8/2021 | | | SD | L | 3-7 | | Gausman, K | R | Gausman, K | | Musgrove, J | R |
| 5/9/2021 | | | SD | W | 4-1 | | Cueto, J | R | Cueto, J | McGee, J | Paddack, C | R |
| 5/10/2021 | | | Tex | L | 4-7 | | Wood, A | L | Wood, A | | Gibson, K | R |
| 5/11/2021 | | | Tex | W | 8-2 | | Webb, L | R | Webb, L | | Lyles, J | R |
| 5/13/2021 | | @ | Pit | W | 4-0 | | DeSclafani, A | R | DeSclafani, A | | Crowe, W | R |
| 5/14/2021 | | @ | Pit | W | 9-0 | | Gausman, K | R | Gausman, K | | Yajure, M | R |
| 5/15/2021 | | @ | Pit | L | 2-3 | | Cueto, J | R | Rogers, T | | Anderson, T | L |
| 5/16/2021 | | @ | Pit | W | 2-0 | | Wood, A | L | Wood, A | McGee, J | Keller, M | R |
| 5/17/2021 | | @ | Cin | L | 3-5 | | Webb, L | R | Webb, L | | Gray, S | R |
| 5/18/2021 | | @ | Cin | W | 11-9 | | DeSclafani, A | R | DeSclafani, A | McGee, J | Castillo, L | R |
| 5/19/2021 | | @ | Cin | W | 6-1 | | Gausman, K | R | Gausman, K | | Miley, W | L |
| 5/20/2021 | | @ | Cin | L | 5-9 | | Cueto, J | R | Cueto, J | | Mahle, T | R |
| 5/21/2021 | | | LAN | L | 3-5 | | Wood, A | L | Wood, A | | Bauer, T | R |
| 5/22/2021 | | | LAN | W | 5-4 | | Kazmir, S | L | Kazmir, S | McGee, J | Buehler, W | R |
| 5/23/2021 | | | LAN | W | 6-5 | 10 | DeSclafani, A | R | Littell, Z | | Urias, J | L |
| 5/25/2021 | | @ | Ari | W | 22-0 | | Gausman, K | R | Gausman, K | | Martin, C | R |
| 5/26/2021 | | @ | Ari | W | 5-1 | | Cueto, J | R | Cueto, J | | Kelly, M | R |
| 5/27/2021 | | @ | LAN | W | 6-3 | | Wood, A | L | Wood, A | McGee, J | Price, D | L |
| 5/28/2021 | | @ | LAN | L | 2-5 | | DeSclafani, A | R | DeSclafani, A | | Buehler, W | R |
| 5/29/2021 | | @ | LAN | L | 3-4 | | Webb, L | R | Garcia, J | | Urias, J | L |
| 5/30/2021 | | @ | LAN | L | 1-2 | | Gausman, K | R | Tropeano, N | | Kershaw, C | L |
| 5/31/2021 | | | LAA | W | 11-2 | | Cueto, J | R | Cueto, J | | Bundy, D | R |
| 6/1/2021 | | | LAA | L | 3-7 | | Wood, A | L | Wood, A | | Heaney, A | L |
| 6/3/2021 | | | ChN | W | 5-3 | | DeSclafani, A | R | DeSclafani, A | McGee, J | Davies, Z | R |
| 6/4/2021 | | | ChN | L | 5-7 | | Kazmir, S | L | Kazmir, S | | Arrieta, J | R |
| 6/5/2021 | | | ChN | W | 5-3 | | Gausman, K | R | Garcia, J | McGee, J | Stewart, K | R |
| 6/6/2021 | | | ChN | L | 4-5 | | Cueto, J | R | Cueto, J | | Hendricks, K | R |
| 6/8/2021 | | @ | Tex | L | 4-5 | | Wood, A | L | Littell, Z | | Lyles, J | R |
| 6/9/2021 | | @ | Tex | W | 4-0 | | Littell, Z | R | Long, S | | Gibson, K | R |
| 6/11/2021 | | @ | Was | L | 2-9 | | DeSclafani, A | R | DeSclafani, A | | Scherzer, M | R |
| 6/12/2021 | 1 | @ | Was | L | 1-2 | 7 | Gausman, K | R | Gausman, K | | Fedde, E | R |
| 6/12/2021 | 2 | @ | Was | W | 5-4 | 7 | Menez, C | L | Leone, D | McGee, J | Rodriguez, J | R |
| 6/13/2021 | | @ | Was | W | 3-2 | 10 | Cueto, J | R | McGee, J | Rogers, T | Ross, J | R |
| 6/14/2021 | | | Ari | W | 10-7 | | Wood, A | L | Alvarez, J | Garcia, J | Peacock, M | R |
| 6/15/2021 | | | Ari | W | 8-3 | | Littell, Z | R | Long, S | | Young, A | L |
| 6/16/2021 | | | Ari | W | 8-7 | | DeSclafani, A | R | Menez, C | | Kelly, M | R |
| 6/17/2021 | | | Ari | W | 8-4 | | Gausman, K | R | McGee, J | | Gallen, Z | R |
| 6/18/2021 | | | Phi | W | 6-4 | | Cueto, J | R | Cueto, J | Rogers, T | Velasquez, V | R |
| 6/19/2021 | | | Phi | W | 5-3 | 10 | Wood, A | L | Littell, Z | | Nola, A | R |
| 6/20/2021 | | | Phi | W | 4-1 | | Long, S | L | Long, S | McGee, J | Eflin, Z | R |
| 6/22/2021 | | @ | LAA | W | 5-1 | | DeSclafani, A | R | DeSclafani, A | | Heaney, A | L |
| 6/23/2021 | | @ | LAA | W | 7-1 | | Gausman, K | R | Gausman, K | | Ohtani, S | R |
| 6/25/2021 | | | Oak | L | 2-7 | | Cueto, J | R | Cueto, J | | Manaea, S | L |
| 6/26/2021 | | | Oak | L | 2-10 | | Wood, A | L | Wood, A | | Montas, F | R |
| 6/27/2021 | | | Oak | L | 0-3 | | Long, S | L | Long, S | | Irvin, C | L |
| 6/28/2021 | | @ | LAN | W | 4-3 | | DeSclafani, A | R | DeSclafani, A | McGee, J | Bauer, T | R |
| 6/29/2021 | | @ | LAN | L | 1-2 | | Gausman, K | R | Gausman, K | | Buehler, W | R |
| 7/1/2021 | | @ | Ari | W | 12-4 | | Cueto, J | R | Cueto, J | | Kelly, M | R |
| 7/2/2021 | | @ | Ari | W | 6-2 | | Wood, A | L | Littell, Z | | Gallen, Z | R |
| 7/3/2021 | | @ | Ari | L | 6-7 | | Long, S | L | Littell, Z | | Faria, J | R |
| 7/4/2021 | | @ | Ari | L | 2-3 | | DeSclafani, A | R | McGee, J | | Smith, C | L |
| 7/5/2021 | | | StL | W | 4-2 | 10 | Gausman, K | R | Alvarez, J | | Kim, K | L |
| 7/6/2021 | | | StL | L | 2-8 | | Cueto, J | R | Cueto, J | | Wainwright, A | R |
| 7/7/2021 | | | StL | W | 7-6 | | Wood, A | L | Rogers, T | McGee, J | Oviedo, J | R |
| 7/9/2021 | | | Was | W | 6-4 | | Webb, L | R | Rogers, T | McGee, J | Espino, P | R |
| 7/10/2021 | | | Was | W | 3-0 | | DeSclafani, A | R | DeSclafani, A | McGee, J | Lester, J | L |
| 7/11/2021 | | | Was | L | 0-2 | | Gausman, K | R | Gausman, K | | Fedde, E | R |
| 7/16/2021 | | @ | StL | L | 8-9 | 11 | Webb, L | R | Baragar, C | | Wainwright, A | R |
| 7/17/2021 | | @ | StL | L | 3-4 | | DeSclafani, A | R | Rogers, T | | Kim, K | L |
| 7/18/2021 | | @ | StL | L | 2-5 | | Cueto, J | R | Cueto, J | | LeBlanc, W | L |
| 7/19/2021 | | @ | LAN | W | 1-0 | | Gausman, K | R | Littell, Z | McGee, J | Gonsolin, T | R |
| 7/20/2021 | | @ | LAN | L | 3-6 | | Wood, A | L | Wood, A | | Nunez, D | L |
| 7/21/2021 | | @ | LAN | W | 9-5 | | Webb, L | R | Alvarez, J | | Urias, J | L |
| 7/22/2021 | | @ | LAN | L | 0-2 | | DeSclafani, A | R | DeSclafani, A | | Buehler, W | R |
| 7/23/2021 | | | Pit | W | 5-2 | | Cueto, J | R | Cueto, J | McGee, J | Kuhl, C | R |
| 7/24/2021 | | | Pit | W | 6-0 | | Gausman, K | R | Gausman, K | | Crowe, W | R |
| 7/25/2021 | | | Pit | W | 3-2 | | Wood, A | L | Leone, D | | Brubaker, J | R |
| 7/27/2021 | | | LAN | W | 9-1 | | Webb, L | R | Webb, L | | Urias, J | L |
| 7/28/2021 | | | LAN | L | 4-8 | | DeSclafani, A | R | DeSclafani, A | | Buehler, W | R |
| 7/29/2021 | | | LAN | L | 2-4 | | Cueto, J | R | McGee, J | | Price, D | L |
| 7/30/2021 | | | Hou | L | 5-6 | | Gausman, K | R | Gausman, K | | Valdez, F | L |
| 7/31/2021 | | | Hou | W | 7-0 | | Wood, A | L | Wood, A | | Greinke, Z | R |
| 8/1/2021 | | | Hou | W | 5-3 | | Webb, L | R | Leone, D | McGee, J | Garcia, L | R |
| 8/2/2021 | | @ | Ari | W | 9-7 | 11 | DeSclafani, A | R | Jackson, J | McGee, J | Widener, T | R |
| 8/3/2021 | | @ | Ari | L | 4-6 | | Cueto, J | R | Cueto, J | | Bumgarner, M | L |
| 8/4/2021 | | @ | Ari | L | 4-5 | | Gausman, K | R | Gausman, K | | Gallen, Z | R |
| 8/5/2021 | | @ | Ari | L | 6-8 | | Wood, A | L | Wood, A | | Kelly, M | R |
| 8/6/2021 | | @ | Mil | W | 5-3 | 10 | Webb, L | R | Alvarez, J | McGee, J | Burnes, C | R |
| 8/7/2021 | | @ | Mil | L | 1-2 | 10 | Sanchez, A | R | Leone, D | | Woodruff, B | R |
| 8/8/2021 | | @ | Mil | L | 4-6 | | Cueto, J | R | Cueto, J | | Anderson, B | L |
| 8/10/2021 | | | Ari | W | 16-3 | | Wood, A | L | Wood, A | | Gallen, Z | R |
| 8/11/2021 | | | Ari | W | 7-4 | | Gausman, K | R | Gausman, K | Rogers, T | Kelly, M | R |
| 8/12/2021 | | | Col | W | 5-2 | | Webb, L | R | Webb, L | McGee, J | Marquez, G | R |
| 8/13/2021 | | | Col | W | 8-4 | | DeSclafani, A | R | DeSclafani, A | | Gomber, A | L |
| 8/14/2021 | | | Col | W | 7-5 | | Long, S | L | Long, S | Rogers, T | Freeland, K | L |
| 8/15/2021 | | | Col | W | 7-6 | 10 | Wood, A | L | McGee, J | | Gray, J | R |
| 8/16/2021 | | | NYN | W | 5-1 | | Gausman, K | R | Gausman, K | | Hill, R | L |
| 8/17/2021 | | | NYN | W | 1-0 | | Webb, L | R | Webb, L | McGee, J | Stroman, M | R |
| 8/18/2021 | | | NYN | L | 2-7 | | DeSclafani, A | R | DeSclafani, A | | Megill, T | R |
| 8/20/2021 | | @ | Oak | W | 5-0 | | Wood, A | L | Wood, A | | Kaprielian, J | R |
| 8/21/2021 | | @ | Oak | W | 11-5 | | Gausman, K | R | Gausman, K | | Manaea, S | L |
| 8/22/2021 | | @ | Oak | L | 7-9 | 10 | Webb, L | R | McGee, J | | Montas, F | R |
| 8/24/2021 | | @ | NYN | W | 10-6 | | Long, S | L | Watson, T | | Megill, T | R |
| 8/25/2021 | | @ | NYN | W | 9-5 | | Cueto, J | R | Cueto, J | | Walker, T | R |
| 8/26/2021 | | @ | NYN | L | 2-4 | | Wood, A | L | Wood, A | | Carrasco, C | R |
| 8/27/2021 | | @ | Atl | W | 6-3 | | Gausman, K | R | Littell, Z | McGee, J | Fried, M | L |
| 8/28/2021 | | @ | Atl | L | 1-7 | | Webb, L | R | Webb, L | | Ynoa, H | R |
| 8/29/2021 | | @ | Atl | W | 9-5 | | DeSclafani, A | R | DeSclafani, A | | Anderson, I | R |
| 8/30/2021 | | | Mil | W | 2-1 | | Alvarez, J | L | Rogers, T | | Burnes, C | R |
| 8/31/2021 | | | Mil | L | 1-8 | | Cueto, J | R | Cueto, J | | Woodruff, B | R |
| 9/1/2021 | | | Mil | W | 7-5 | | Gausman, K | R | Gausman, K | McGee, J | Anderson, B | L |
| 9/2/2021 | | | Mil | W | 5-3 | | Webb, L | R | Webb, L | Rogers, T | Lauer, E | L |
| 9/3/2021 | | | LAN | L | 4-7 | | DeSclafani, A | R | Quintana, J | | Knebel, C | R |
| 9/4/2021 | | | LAN | W | 6-5 | | Jackson, J | R | McGee, J | | Urias, J | L |
| 9/5/2021 | | | LAN | L | 2-7 | | Leone, D | R | Leone, D | | Buehler, W | R |
| 9/6/2021 | | @ | Col | W | 11-2 | | Gausman, K | R | Gausman, K | | Freeland, K | L |
| 9/7/2021 | | @ | Col | W | 3-2 | | Webb, L | R | Webb, L | McGee, J | Gonzalez, C | R |
| 9/8/2021 | | @ | Col | W | 9-1 | | DeSclafani, A | R | DeSclafani, A | | Gray, J | R |
| 9/10/2021 | | @ | ChN | W | 4-3 | 10 | Leone, D | R | Doval, C | McGee, J | Hendricks, K | R |
| 9/11/2021 | | @ | ChN | W | 5-3 | | Gausman, K | R | Alvarez, J | Rogers, T | Davies, Z | R |
| 9/12/2021 | | @ | ChN | L | 3-4 | | Webb, L | R | Webb, L | | Steele, J | L |
| 9/13/2021 | | | SD | W | 3-2 | | Leone, D | R | Rogers, T | | Darvish, Y | R |
| 9/14/2021 | | | SD | W | 11-10 | | DeSclafani, A | R | Castro, K | Doval, C | Arrieta, J | R |
| 9/15/2021 | | | SD | W | 2-0 | | Leone, D | R | Watson, T | Rogers, T | Musgrove, J | R |
| 9/16/2021 | | | SD | W | 6-5 | | Gausman, K | R | Watson, T | Littell, Z | Johnson, P | R |
| 9/17/2021 | | | Atl | W | 8-2 | | Webb, L | R | Webb, L | | Anderson, I | R |
| 9/18/2021 | | | Atl | W | 9-8 | | Wood, A | L | Leone, D | | Morton, C | R |
| 9/19/2021 | | | Atl | L | 1-5 | | DeSclafani, A | R | DeSclafani, A | | Fried, M | L |
| 9/21/2021 | | @ | SD | L | 6-7 | 11 | Gausman, K | R | Watson, T | | Musgrove, J | R |
| 9/22/2021 | | @ | SD | L | 6-8 | | Kazmir, S | L | Castro, K | | Velasquez, V | R |
| 9/23/2021 | | @ | SD | W | 12-5 | | Webb, L | R | Webb, L | | Darvish, Y | R |
| 9/24/2021 | | @ | Col | W | 15-10 | | Wood, A | L | Wood, A | | Lambert, P | R |
| 9/25/2021 | | @ | Col | L | 0-6 | | DeSclafani, A | R | DeSclafani, A | | Gray, J | R |
| 9/26/2021 | | @ | Col | L | 1-6 | | Gausman, K | R | Gausman, K | | Senzatela, A | R |
| 9/28/2021 | | | Ari | W | 8-7 | 10 | Webb, L | R | Doval, C | | Weaver, L | R |
| 9/29/2021 | | | Ari | W | 3-1 | | Wood, A | L | Wood, A | Rogers, T | Kelly, M | R |
| 9/30/2021 | | | Ari | W | 10-2 | | Kazmir, S | L | Kazmir, S | | Bumgarner, M | L |
| 10/1/2021 | | | SD | L | 1-7 | | DeSclafani, A | R | DeSclafani, A | | Avila, P | R |
| 10/2/2021 | | | SD | W | 5-4 | | Gausman, K | R | Gausman, K | Leone, D | Musgrove, J | R |
| 10/3/2021 | | | SD | L | 2-3 | 10 | Webb, L | R | McGee, J | | Knehr, R | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/1/2021 | | @ | Sea | W | Posey, B | 5 | 3 | 1 | 0 | 1.000 | 1-0 | W1 | 1 |
| 4/2/2021 | | @ | Sea | W | Ruf, D | 6 | 5 | 2 | 0 | 1.000 | 2-0 | W2 | 2 |
| 4/3/2021 | | @ | Sea | W | Yastrzemski, M | 6 | 1 | 3 | 0 | 1.000 | 3-0 | W3 | 3 |
| 4/5/2021 | | @ | SD | W | Longoria, E | 12 | 6 | 4 | 0 | 1.000 | 4-0 | W4 | 4 |
| 4/6/2021 | | @ | SD | W | Flores, W | 3 | 2 | 5 | 0 | 1.000 | 5-0 | W5 | 5 |
| 4/7/2021 | | @ | SD | W | Longoria, E | 6 | 2 | 6 | 0 | 1.000 | 6-0 | W6 | 6 |
| 4/9/2021 | | | Col | L | | 2 | 7 | 6 | 1 | .857 | 6-1 | L1 | 7 |
| 4/10/2021 | | | Col | W | Longoria, E | 3 | 2 | 7 | 1 | .875 | 7-1 | W1 | 8 |
| 4/11/2021 | | | Col | W | Belt, B | 7 | 0 | 8 | 1 | .889 | 8-1 | W2 | 9 |
| 4/12/2021 | | | Cin | L | | 0 | 1 | 8 | 2 | .800 | 8-2 | L1 | 10 |
| 4/13/2021 | | | Cin | W | Posey, B | 4 | 0 | 9 | 2 | .818 | 8-2 | W1 | 11 |
| 4/14/2021 | | | Cin | W | Belt, B | 14 | 2 | 10 | 2 | .833 | 8-2 | W2 | 12 |
| 4/16/2021 | | @ | Mia | W | Solano, D | 9 | 5 | 11 | 2 | .846 | 8-2 | W3 | 13 |
| 4/17/2021 | | @ | Mia | L | | 4 | 8 | 11 | 3 | .786 | 7-3 | L1 | 14 |
| 4/18/2021 | | @ | Mia | W | La Stella, T | 6 | 1 | 12 | 3 | .800 | 7-3 | W1 | 15 |
| 4/19/2021 | | @ | Phi | W | Yastrzemski, M | 8 | 6 | 13 | 3 | .813 | 7-3 | W2 | 16 |
| 4/20/2021 | | @ | Phi | W | Belt, B | 7 | 3 | 14 | 3 | .824 | 8-2 | W3 | 17 |
| 4/21/2021 | | @ | Phi | L | | 3 | 4 | 14 | 4 | .778 | 7-3 | L1 | 18 |
| 4/22/2021 | | | Mia | L | | 0 | 1 | 14 | 5 | .737 | 6-4 | L2 | 19 |
| 4/23/2021 | | | Mia | W | Belt, B | 7 | 1 | 15 | 5 | .750 | 7-3 | W1 | 20 |
| 4/24/2021 | | | Mia | W | Dickerson, A | 6 | 5 | 16 | 5 | .762 | 7-3 | W2 | 21 |
| 4/25/2021 | | | Mia | L | | 5 | 8 | 16 | 6 | .727 | 6-4 | L1 | 22 |
| 4/26/2021 | | | Col | W | Longoria, E | 5 | 4 | 17 | 6 | .739 | 6-4 | W1 | 23 |
| 4/27/2021 | | | Col | L | | 3 | 9 | 17 | 7 | .708 | 6-4 | L1 | 24 |
| 4/28/2021 | | | Col | W | Longoria, E | 2 | 1 | 18 | 7 | .720 | 6-4 | W1 | 25 |
| 4/30/2021 | | @ | SD | W | Duggar, S | 3 | 1 | 19 | 7 | .731 | 6-4 | W2 | 26 |
| 5/1/2021 | | @ | SD | W | Posey, B | 12 | 6 | 20 | 7 | .741 | 6-4 | W3 | 27 |
| 5/2/2021 | | @ | SD | W | Tauchman, M | 3 | 1 | 21 | 7 | .750 | 7-3 | W4 | 28 |
| 5/4/2021 | 1 | @ | Col | L | | 4 | 6 | 21 | 8 | .724 | 7-3 | L1 | 29 |
| 5/4/2021 | 2 | @ | Col | W | Dubon, M | 1 | 0 | 22 | 8 | .733 | 7-3 | W1 | 30 |
| 5/5/2021 | | @ | Col | L | | 1 | 2 | 22 | 9 | .710 | 6-4 | L1 | 31 |
| 5/7/2021 | | | SD | W | Ruf, D | 5 | 3 | 23 | 9 | .719 | 7-3 | W1 | 32 |
| 5/8/2021 | | | SD | L | | 3 | 7 | 23 | 10 | .697 | 6-4 | L1 | 33 |
| 5/9/2021 | | | SD | W | Posey, B | 4 | 1 | 24 | 10 | .706 | 7-3 | W1 | 34 |
| 5/10/2021 | | | Tex | L | | 4 | 7 | 24 | 11 | .686 | 6-4 | L1 | 35 |
| 5/11/2021 | | | Tex | W | Longoria, E | 8 | 2 | 25 | 11 | .694 | 6-4 | W1 | 36 |
| 5/13/2021 | | @ | Pit | W | Tauchman, M | 4 | 0 | 26 | 11 | .703 | 6-4 | W2 | 37 |
| 5/14/2021 | | @ | Pit | W | Posey, B | 9 | 0 | 27 | 11 | .711 | 6-4 | W3 | 38 |
| 5/15/2021 | | @ | Pit | L | | 2 | 3 | 27 | 12 | .692 | 6-4 | L1 | 39 |
| 5/16/2021 | | @ | Pit | W | Dubon, M | 2 | 0 | 28 | 12 | .700 | 6-4 | W1 | 40 |
| 5/17/2021 | | @ | Cin | L | | 3 | 5 | 28 | 13 | .683 | 6-4 | L1 | 41 |
| 5/18/2021 | | @ | Cin | W | Dickerson, A | 11 | 9 | 29 | 13 | .690 | 6-4 | W1 | 42 |
| 5/19/2021 | | @ | Cin | W | Longoria, E | 6 | 1 | 30 | 13 | .698 | 7-3 | W2 | 43 |
| 5/20/2021 | | @ | Cin | L | | 5 | 9 | 30 | 14 | .682 | 6-4 | L1 | 44 |
| 5/21/2021 | | | LAN | L | | 3 | 5 | 30 | 15 | .667 | 6-4 | L2 | 45 |
| 5/22/2021 | | | LAN | W | Belt, B | 5 | 4 | 31 | 15 | .674 | 6-4 | W1 | 46 |
| 5/23/2021 | | | LAN | W | Dubon, M | 6 | 5 | 32 | 15 | .681 | 6-4 | W2 | 47 |
| 5/25/2021 | | @ | Ari | W | Longoria, E | 22 | 0 | 33 | 15 | .688 | 6-4 | W3 | 48 |
| 5/26/2021 | | @ | Ari | W | Dickerson, A | 5 | 1 | 34 | 15 | .694 | 7-3 | W4 | 49 |
| 5/27/2021 | | @ | LAN | W | Longoria, E | 6 | 3 | 35 | 15 | .700 | 7-3 | W5 | 50 |
| 5/28/2021 | | @ | LAN | L | | 2 | 5 | 35 | 16 | .686 | 7-3 | L1 | 51 |
| 5/29/2021 | | @ | LAN | L | | 3 | 4 | 35 | 17 | .673 | 6-4 | L2 | 52 |
| 5/30/2021 | | @ | LAN | L | | 1 | 2 | 35 | 18 | .660 | 5-5 | L3 | 53 |
| 5/31/2021 | | | LAA | W | Dickerson, A | 11 | 2 | 36 | 18 | .667 | 6-4 | W1 | 54 |
| 6/1/2021 | | | LAA | L | | 3 | 7 | 36 | 19 | .655 | 6-4 | L1 | 55 |
| 6/3/2021 | | | ChN | W | Flores, W | 5 | 3 | 37 | 19 | .661 | 6-4 | W1 | 56 |
| 6/4/2021 | | | ChN | L | | 5 | 7 | 37 | 20 | .649 | 5-5 | L1 | 57 |
| 6/5/2021 | | | ChN | W | Slater, A | 5 | 3 | 38 | 20 | .655 | 5-5 | W1 | 58 |
| 6/6/2021 | | | ChN | L | | 4 | 5 | 38 | 21 | .644 | 4-6 | L1 | 59 |
| 6/8/2021 | | @ | Tex | L | | 4 | 5 | 38 | 22 | .633 | 3-7 | L2 | 60 |
| 6/9/2021 | | @ | Tex | W | Belt, B | 4 | 0 | 39 | 22 | .639 | 4-6 | W1 | 61 |
| 6/11/2021 | | @ | Was | L | | 2 | 9 | 39 | 23 | .629 | 4-6 | L1 | 62 |
| 6/12/2021 | 1 | @ | Was | L | | 1 | 2 | 39 | 24 | .619 | 4-6 | L2 | 63 |
| 6/12/2021 | 2 | @ | Was | W | Dubon, M | 5 | 4 | 40 | 24 | .625 | 4-6 | W1 | 64 |
| 6/13/2021 | | @ | Was | W | Crawford, B | 3 | 2 | 41 | 24 | .631 | 5-5 | W2 | 65 |
| 6/14/2021 | | | Ari | W | Slater, A | 10 | 7 | 42 | 24 | .636 | 5-5 | W3 | 66 |
| 6/15/2021 | | | Ari | W | Belt, B | 8 | 3 | 43 | 24 | .642 | 6-4 | W4 | 67 |
| 6/16/2021 | | | Ari | W | Solano, D | 8 | 7 | 44 | 24 | .647 | 6-4 | W5 | 68 |
| 6/17/2021 | | | Ari | W | Yastrzemski, M | 8 | 4 | 45 | 24 | .652 | 7-3 | W6 | 69 |
| 6/18/2021 | | | Phi | W | Flores, W | 6 | 4 | 46 | 24 | .657 | 8-2 | W7 | 70 |
| 6/19/2021 | | | Phi | W | Duggar, S | 5 | 3 | 47 | 24 | .662 | 8-2 | W8 | 71 |
| 6/20/2021 | | | Phi | W | Flores, W | 4 | 1 | 48 | 24 | .667 | 9-1 | W9 | 72 |
| 6/22/2021 | | @ | LAA | W | Ruf, D | 5 | 1 | 49 | 24 | .671 | 10-0 | W10 | 73 |
| 6/23/2021 | | @ | LAA | W | Posey, B | 7 | 1 | 50 | 24 | .676 | 10-0 | W11 | 74 |
| 6/25/2021 | | | Oak | L | | 2 | 7 | 50 | 25 | .667 | 9-1 | L1 | 75 |
| 6/26/2021 | | | Oak | L | | 2 | 10 | 50 | 26 | .658 | 8-2 | L2 | 76 |
| 6/27/2021 | | | Oak | L | | 0 | 3 | 50 | 27 | .649 | 7-3 | L3 | 77 |
| 6/28/2021 | | @ | LAN | W | Duggar, S | 4 | 3 | 51 | 27 | .654 | 7-3 | W1 | 78 |
| 6/29/2021 | | @ | LAN | L | | 1 | 2 | 51 | 28 | .646 | 6-4 | L1 | 79 |
| 7/1/2021 | | @ | Ari | W | Duggar, S | 12 | 4 | 52 | 28 | .650 | 6-4 | W1 | 80 |
| 7/2/2021 | | @ | Ari | W | Yastrzemski, M | 6 | 2 | 53 | 28 | .654 | 6-4 | W2 | 81 |
| 7/3/2021 | | @ | Ari | L | | 6 | 7 | 53 | 29 | .646 | 5-5 | L1 | 82 |
| 7/4/2021 | | @ | Ari | L | | 2 | 3 | 53 | 30 | .639 | 4-6 | L2 | 83 |
| 7/5/2021 | | | StL | W | Ruf, D | 4 | 2 | 54 | 30 | .643 | 4-6 | W1 | 84 |
| 7/6/2021 | | | StL | L | | 2 | 8 | 54 | 31 | .635 | 4-6 | L1 | 85 |
| 7/7/2021 | | | StL | W | Flores, W | 7 | 6 | 55 | 31 | .640 | 5-5 | W1 | 86 |
| 7/9/2021 | | | Was | W | Casali, C | 6 | 4 | 56 | 31 | .644 | 6-4 | W2 | 87 |
| 7/10/2021 | | | Was | W | Yastrzemski, M | 3 | 0 | 57 | 31 | .648 | 6-4 | W3 | 88 |
| 7/11/2021 | | | Was | L | | 0 | 2 | 57 | 32 | .640 | 6-4 | L1 | 89 |
| 7/16/2021 | | @ | StL | L | | 8 | 9 | 57 | 33 | .633 | 5-5 | L2 | 90 |
| 7/17/2021 | | @ | StL | L | | 3 | 4 | 57 | 34 | .626 | 4-6 | L3 | 91 |
| 7/18/2021 | | @ | StL | L | | 2 | 5 | 57 | 35 | .620 | 4-6 | L4 | 92 |
| 7/19/2021 | | @ | LAN | W | Dickerson, A | 1 | 0 | 58 | 35 | .624 | 5-5 | W1 | 93 |
| 7/20/2021 | | @ | LAN | L | | 3 | 6 | 58 | 36 | .617 | 4-6 | L1 | 94 |
| 7/21/2021 | | @ | LAN | W | | 9 | 5 | 59 | 36 | .621 | 5-5 | W1 | 95 |
| 7/22/2021 | | @ | LAN | L | | 0 | 2 | 59 | 37 | .615 | 4-6 | L1 | 96 |
| 7/23/2021 | | | Pit | W | Wade, L | 5 | 2 | 60 | 37 | .619 | 4-6 | W1 | 97 |
| 7/24/2021 | | | Pit | W | Posey, B | 6 | 0 | 61 | 37 | .622 | 4-6 | W2 | 98 |
| 7/25/2021 | | | Pit | W | Yastrzemski, M | 3 | 2 | 62 | 37 | .626 | 5-5 | W3 | 99 |
| 7/27/2021 | | | LAN | W | Wade, L | 9 | 1 | 63 | 37 | .630 | 6-4 | W4 | 100 |
| 7/28/2021 | | | LAN | L | | 4 | 8 | 63 | 38 | .624 | 6-4 | L1 | 101 |
| 7/29/2021 | | | LAN | L | | 2 | 4 | 63 | 39 | .618 | 6-4 | L2 | 102 |
| 7/30/2021 | | | Hou | L | | 5 | 6 | 63 | 40 | .612 | 5-5 | L3 | 103 |
| 7/31/2021 | | | Hou | W | Ruf, D | 7 | 0 | 64 | 40 | .615 | 6-4 | W1 | 104 |
| 8/1/2021 | | | Hou | W | Yastrzemski, M | 5 | 3 | 65 | 40 | .619 | 6-4 | W2 | 105 |
| 8/2/2021 | | @ | Ari | W | Yastrzemski, M | 9 | 7 | 66 | 40 | .623 | 7-3 | W3 | 106 |
| 8/3/2021 | | @ | Ari | L | | 4 | 6 | 66 | 41 | .617 | 6-4 | L1 | 107 |
| 8/4/2021 | | @ | Ari | L | | 4 | 5 | 66 | 42 | .611 | 5-5 | L2 | 108 |
| 8/5/2021 | | @ | Ari | L | | 6 | 8 | 66 | 43 | .606 | 4-6 | L3 | 109 |
| 8/6/2021 | | @ | Mil | W | Flores, W | 5 | 3 | 67 | 43 | .609 | 4-6 | W1 | 110 |
| 8/7/2021 | | @ | Mil | L | | 1 | 2 | 67 | 44 | .604 | 4-6 | L1 | 111 |
| 8/8/2021 | | @ | Mil | L | | 4 | 6 | 67 | 45 | .598 | 4-6 | L2 | 112 |
| 8/10/2021 | | | Ari | W | Belt, B | 16 | 3 | 68 | 45 | .602 | 5-5 | W1 | 113 |
| 8/11/2021 | | | Ari | W | Crawford, B | 7 | 4 | 69 | 45 | .605 | 5-5 | W2 | 114 |
| 8/12/2021 | | | Col | W | Dickerson, A | 5 | 2 | 70 | 45 | .609 | 5-5 | W3 | 115 |
| 8/13/2021 | | | Col | W | Flores, W | 8 | 4 | 71 | 45 | .612 | 5-5 | W4 | 116 |
| 8/14/2021 | | | Col | W | Slater, A | 7 | 5 | 72 | 45 | .615 | 6-4 | W5 | 117 |
| 8/15/2021 | | | Col | W | Longoria, E | 7 | 6 | 73 | 45 | .619 | 7-3 | W6 | 118 |
| 8/16/2021 | | | NYN | W | Posey, B | 5 | 1 | 74 | 45 | .622 | 8-2 | W7 | 119 |
| 8/17/2021 | | | NYN | W | Belt, B | 1 | 0 | 75 | 45 | .625 | 8-2 | W8 | 120 |
| 8/18/2021 | | | NYN | L | | 2 | 7 | 75 | 46 | .620 | 8-2 | L1 | 121 |
| 8/20/2021 | | @ | Oak | W | Bryant, K | 5 | 0 | 76 | 46 | .623 | 9-1 | W1 | 122 |
| 8/21/2021 | | @ | Oak | W | Flores, W | 11 | 5 | 77 | 46 | .626 | 9-1 | W2 | 123 |
| 8/22/2021 | | @ | Oak | L | | 7 | 9 | 77 | 47 | .621 | 8-2 | L1 | 124 |
| 8/24/2021 | | @ | NYN | W | Flores, W | 10 | 6 | 78 | 47 | .624 | 8-2 | W1 | 125 |
| 8/25/2021 | | @ | NYN | W | Yastrzemski, M | 9 | 5 | 79 | 47 | .627 | 8-2 | W2 | 126 |
| 8/26/2021 | | @ | NYN | L | | 2 | 4 | 79 | 48 | .622 | 7-3 | L1 | 127 |
| 8/27/2021 | | @ | Atl | W | Posey, B | 6 | 3 | 80 | 48 | .625 | 7-3 | W1 | 128 |
| 8/28/2021 | | @ | Atl | L | | 1 | 7 | 80 | 49 | .620 | 6-4 | L1 | 129 |
| 8/29/2021 | | @ | Atl | W | Wade, L | 9 | 5 | 81 | 49 | .623 | 6-4 | W1 | 130 |
| 8/30/2021 | | | Mil | W | Slater, A | 2 | 1 | 82 | 49 | .626 | 7-3 | W2 | 131 |
| 8/31/2021 | | | Mil | L | | 1 | 8 | 82 | 50 | .621 | 6-4 | L1 | 132 |
| 9/1/2021 | | | Mil | W | Posey, B | 7 | 5 | 83 | 50 | .624 | 6-4 | W1 | 133 |
| 9/2/2021 | | | Mil | W | Slater, A | 5 | 3 | 84 | 50 | .627 | 7-3 | W2 | 134 |
| 9/3/2021 | | | LAN | L | | 4 | 7 | 84 | 51 | .622 | 6-4 | L1 | 135 |
| 9/4/2021 | | | LAN | W | Longoria, E | 6 | 5 | 85 | 51 | .625 | 6-4 | W1 | 136 |
| 9/5/2021 | | | LAN | L | | 2 | 7 | 85 | 52 | .620 | 6-4 | L1 | 137 |
| 9/6/2021 | | @ | Col | W | Bryant, K | 11 | 2 | 86 | 52 | .623 | 6-4 | W1 | 138 |
| 9/7/2021 | | @ | Col | W | Crawford, B | 3 | 2 | 87 | 52 | .626 | 7-3 | W2 | 139 |
| 9/8/2021 | | @ | Col | W | Bryant, K | 9 | 1 | 88 | 52 | .629 | 7-3 | W3 | 140 |
| 9/10/2021 | | @ | ChN | W | Yastrzemski, M | 4 | 3 | 89 | 52 | .631 | 7-3 | W4 | 141 |
| 9/11/2021 | | @ | ChN | W | Bryant, K | 5 | 3 | 90 | 52 | .634 | 8-2 | W5 | 142 |
| 9/12/2021 | | @ | ChN | L | | 3 | 4 | 90 | 53 | .629 | 7-3 | L1 | 143 |
| 9/13/2021 | | | SD | W | Ruf, D | 3 | 2 | 91 | 53 | .632 | 7-3 | W1 | 144 |
| 9/14/2021 | | | SD | W | Posey, B | 11 | 10 | 92 | 53 | .634 | 8-2 | W2 | 145 |
| 9/15/2021 | | | SD | W | Longoria, E | 2 | 0 | 93 | 53 | .637 | 8-2 | W3 | 146 |
| 9/16/2021 | | | SD | W | Flores, W | 6 | 5 | 94 | 53 | .639 | 9-1 | W4 | 147 |
| 9/17/2021 | | | Atl | W | Crawford, B | 8 | 2 | 95 | 53 | .642 | 9-1 | W5 | 148 |
| 9/18/2021 | | | Atl | W | | 9 | 8 | 96 | 53 | .644 | 9-1 | W6 | 149 |
| 9/19/2021 | | | Atl | L | | 1 | 5 | 96 | 54 | .640 | 8-2 | L1 | 150 |
| 9/21/2021 | | @ | SD | L | | 6 | 7 | 96 | 55 | .636 | 7-3 | L2 | 151 |
| 9/22/2021 | | @ | SD | L | | 6 | 8 | 96 | 56 | .632 | 6-4 | L3 | 152 |
| 9/23/2021 | | @ | SD | W | Dickerson, A | 12 | 5 | 97 | 56 | .634 | 7-3 | W1 | 153 |
| 9/24/2021 | | @ | Col | W | | 15 | 10 | 98 | 56 | .636 | 7-3 | W2 | 154 |
| 9/25/2021 | | @ | Col | L | | 0 | 6 | 98 | 57 | .632 | 6-4 | L1 | 155 |
| 9/26/2021 | | @ | Col | L | | 1 | 6 | 98 | 58 | .628 | 5-5 | L2 | 156 |
| 9/28/2021 | | | Ari | W | Flores, W | 8 | 7 | 99 | 58 | .631 | 5-5 | W1 | 157 |
| 9/29/2021 | | | Ari | W | Bryant, K | 3 | 1 | 100 | 58 | .633 | 5-5 | W2 | 158 |
| 9/30/2021 | | | Ari | W | Ruf, D | 10 | 2 | 101 | 58 | .635 | 5-5 | W3 | 159 |
| 10/1/2021 | | | SD | L | | 1 | 7 | 101 | 59 | .631 | 5-5 | L1 | 160 |
| 10/2/2021 | | | SD | W | Ruf, D | 5 | 4 | 102 | 59 | .634 | 6-4 | W1 | 161 |
| 10/3/2021 | | | SD | L | | 2 | 3 | 102 | 60 | .630 | 6-4 | L1 | 162 |